Search results for " manifolds" in Articles / App Notes
Article
Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
…(PUPSIT) and a post-use integrity test in situ, the potential for leak development within single-use manifolds during installation or processing, and the need to minimize hold-up volumes, Jackson com…
Article
Technology Innovations Improve Process Chromatography Performance
“The current process technologies, such as functionally closed single-use manifolds for [chromatography] skids, pre-packed columns, and robust sensor components, enable long-term processing in a biobu…
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Biosimilars Development and Supply: How Complex Can the Process Be?
As the complex requirements of manufacturing biologics are manifold, it is important that biomanufacturing companies adopt quality-by-design principles.
Countries around the world face a gro…
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Extractables in Single-Use Systems Used in ADC Manufacturing, Part 2
We performed extractables studies on single-use chromatography and tangential flow filtration systems using common solvents in ADC manufacturing, DMA and DMSO. The low levels of extractables f…
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Industry Adoption of Single-Use Systems Remains Low
Sterile-fluid transfer has traditionally been conducted through product piping, stainless-steel vessels, routing manifolds, and valves--all of which requires cleaning and sterilization. In addition, e…
Article
Impact of Media Components on CQAs of Monoclonal Antibodies
Sodium butyrate and sodium propionate, an alkaloid have been reported to enhance mAb production manifolds (14–16).
Future Perspective
Progress in cell-culture technology has led to substantial e…
Article
Fluid Handling in Biopharma Facilities
Utilizing tubeset manifolds that have been overmolded instead of mechanically fastened can greatly reduce the risk of leaks occurring. Containers should be designed to avoid the generation of holes or…