Search results for " productivity" in Articles / App Notes
Article
The Challenge of Disruptive Technologies in Bioprocessing
“Higher productivity and higher throughput processes that integrate upstream and downstream unit operations are driving technology innovation downstream. Lastly, commercialization of gene and cell the…
Article
Reducing Cross-Contamination Risks in Process Chromatography
“There seems to be wide variation in the use of these tools, depending on facility provenance, number of molecules manufactured, regionalization requirements, drive towards standardization, productiv…
Article
Modular Manufacturing Platforms for Biologics
May 01, 2015
By Randi Hernandez
BioPharm International
Volume 28, Issue 5
It should come as no surprise that the good design principles governing the execution of pharmaceutical manu…
Article
Improving PAT for Biologics
The complexity of biopharma processes requires innovative solutions.
Dec 01, 2014
By Cynthia Challener, PhD
BioPharm International
A key component of the quality-by-design (QbD) ap…
Article
The Affordable Care Act's Impact on Innovation in Biopharma
The biopharmaceutical industry contemplates product innovation within the changing landscape of healthcare.
The Affordable Care Act (ACA) has elicited intense national debate and sent biopharm…
Article
Automated Concentration and Diafiltration of Multiple siRNA Samples
The project objective was to streamline the process to improve process efficiency and productivity while improving product quality.
PROCESS DESCRIPTION
The production of RNA ol…
Article
Cell-free Expression Systems Pose Cell Culture Alternative
Cell-free expression is promising in preclinical applications, but still presents challenges to scale up for commercial production.
Feliza Mirasol
Among the challenges in upstrea…
Article
Good Manufacturing Practices: Challenges with Compliance
WrightStudio/Stock.Adobe.com
The complexity of biologics and the use of new technologies present challenges for complying with CGMPs.
By Lauren Lavelle
…
Article
Optimizing Late-Stage and Commercial Cell-Culture Processes
In Lonza’s experience, increases in viable cell concentration and maintaining high culture viability for longer duration have primarily contributed to productivity increases, rather than improvements …
Article
Lessons Learned Accelerate Vaccine Development
Collaboration and single-use technologies aided the rapid scale-up of Ebola vaccine manufacturing.
By Cynthia A. Challener
Vaccine development is a complicated process that can take many yea…