Search results for " biotherapeutics" in Articles / App Notes

Article Best Practices for Selecting a Top-Quality Cell Line
Irina Shi - Stock.Adobe.com Leveraging automation and a step-by-step approach are keys to success. By Cynthia A. Challener Cell lines determine the performanc…

Article Preclinical Evaluation of Product Related Impurities and Variants
Despite their success, the adoption of biotherapeutics is marred by issues around affordability as well as risks associated to the challenges in assessment of their safety and efficacy arising from th…

Article Labeling of Biosimilars
EMA is under pressure to exert even tighter standards on biosimilars being marketed in Europe. Feb 01, 2015 By Sean Milmo BioPharm International The European Medicines Agency (EMA) has r…

Article CMOs Concerned With Cost of Single-Use Equipment
Suppliers indicate prices for single-use equipment are likely to increase. By Eric Langer Contract manufacturing organizations (CMOs) have been enthusiastic adopters of single-use technologi…

Article CMOs Continue to Improve Overall Biomanufacturing Performance
Better process development is creating industry benchmarks for bioprocessing. By Eric Langer Biomanufacturing efficiency is on everyone’s minds, being the single most important area of focus…

Article Addressing the Challenges in Downstream Processing Today and Tomorrow
In addition to high cell density mammalian expression, expanded utilization of other expression systems such as microbial and yeast will support these newer biotherapeutics (BioTx). The diversity of B…

Article Updating Viral Clearance for New Biologic Modalities
Many of these new and evolving biotherapeutics use viruses or virus-related approaches in their manufacturing processes. Clearance challenges The challenge of demonstrating viral clearance in …

Article Get Acquainted with How SPR Technology is Used for Better Protein Characterization
Surface plasmon resonance (SPR) has become a go-to tool for biotherapeutic characterization, and most approved antibody therapeutics have passed through a Biacore SPR system. Stay up-to-date wit…

Article Continuous Processing for the Production of Biopharmaceuticals
Perfusion technology has been successfully used for the production of biotherapeutics for more than a decade. In the past few years, researchers have worked toward making various downstream unit opera…

Article Are You in Control of the Quality of Your mAbs?
Better biotherapeutic characterization for improved quality control At the recent WCBP conference in Washington, D.C., Dr. Stuart Knowling from Antibody Analytics presented how the latest innovati…

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