Search results for " cost" in Articles / App Notes
Article
Development of Purification for Challenging Fc-Fusion Proteins
Advantages can include higher process capacity, smaller column size, shorter cycle time, and, in most instances, lower manufacturing cost. Smaller buffer volume is also typically required, which may c…
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Bioburden Control in the Biopharmaceutical Industry
Biologics manufacturing, however, costs more than small-molecule drug manufacturing in terms of research, investments, installations, maintenances, facilities, and technologies.
Microbial conta…
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Avoiding Investigational Failures and Discrepancies
Be aware, however, of an investigational truism that many working in regulatory environments have learned the hard way: for every solution, there is a cost. As such, several questions need to be taken…
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Contract Manufacturing Through the Years
That enabled the bio/pharmaceutical companies to rid themselves of the assets without negative publicity and costly labor settlements.
A second factor was the explosion of early stage bio/…
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Hybrid Bioprocessing: A Q&A with Andrew Sinclair
…re attributed to what are described as single use facilities but are in fact hybrid; they have lower costs, smaller footprints less support infrastructure, but they still have some reusable equipment…
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Being Thorough When Transferring Technology
Interpreting a good run as a reproducible run can be a costly mistake, so it is important to include as much data from previous development runs and/or at-scale batches when outsourcing projects. Many…
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Mechanistic Modeling of Preparative Ion-Exchange Chromatography
Models can also be judiciously used to reduce lab experimentation, thereby significantly reducing the time required and the cost incurred during process development. With the advent of quality by desi…
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Speed and Flexibility Are Dual Goals for Biopharma Operations
…nd Bio-Process Systems Alliance, are addressing concerns about extractables and leachables, disposal costs, and sustainability.
The use of modeling to develop bioprocessing operations and systems…
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Reconciling Sensor Communication Gaps
Expression is “where the action is—where throughput and volumetric productivity exert the greatest influence on cost of goods.cleaning validation, and calibration.
The desirability of platform pur…
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Drug Quality Key to Innovation and Access
The demand for affordable personalized, or precision, medicines to treat lethal diseases requires efficient and cost-effective operations that promote innovation and avoid shortages. Similarly, modern…