Search results for " perfusion" in Articles / App Notes
Article
Technology Innovations Improve Process Chromatography Performance
As technology matures, inefficiencies and process limitations in downstream process chromatography are improved.
By Feliza Mirasol
Selecting an appropriate separation technology fo…
Article
Considerations for Optimizing Process Development
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Intensify your cell culture processes to keep pace with today’s industry and regulatory expectations.
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2019’s Top Bioprocessing Trends and What to Expect in 2020
2019 proved to be an exciting year for biopharmaceutical developers and process engineers, filled with both advancements and lessons. Considering how far the industry has come, what direction will 2…
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Process Development and Optimization Using the ReadyToProcess WAVE™ 25 Bioreactor System in Dual Mode
To exemplify the capabilities of the system’s features, four different feeding strategies—bolus, semi continuous, continuous, and perfusion—were used.
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Next Generation Bioprocesses: Mapping Roads to the Future
Increased productivity demand and a diversifying clinical drug pipeline have pushed the industry to explore new strategies and technologies in biomanufacturing. So what are next-generation proc…
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A Plastic Pipeline for Commercial Bioprocessing?
Less than two-thirds use disposable chromatography systems and less than half use disposable perfusion devices.
All product types evaluated in the survey—except sampling systems—ar…
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Making the Move to Continuous Chromatography
Continuous chromatography systems are designed to be loaded continuously, which is a useful approach when the purification step is connected to an upstream perfusion bioreactor. There are several diff…
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What You Need to Know about Continuous Processing
There is a lot of interest around continuous biomanufacturing, and it is expected to have a significant impact on the biomanufacturing industry over the next few years. Continuous processing can hel…
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Impact of Media Components on CQAs of Monoclonal Antibodies
The authors review how media components modulate the quality of monoclonal antibody products.
By Anurag Rathore, Rajinder Kaur, Dipankar Borgayari
Recombinant protein products have…
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
Alternatively, upstream process scale-up can make use of perfusion reactors, which use a constant supply of cell-culture media while removing unwanted byproducts throughout a prolonged production run …