Search results for "antibodies" in Articles / App Notes
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Predicting Progress in Protein Aggregation
As the development of biologic drugs based on antibodies and other protein/peptide molecules continues apace, the control and prevention of aggregation during manufacturing, downstream processing, for…
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Recap: Chromatography + filtration virtual summit 2024
Did you miss the Chromatography + filtration virtual summit 2024? Don’t worry – here are the highlights and session recordings from the event on optimizing purification and filtration for mAbs…
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Detailed agenda for Chromatography + filtration virtual summit
Explore the latest advancements in process development and scale-up
Check out the full agenda below!
Join Cytiva Chromatography and filtration summit online to learn from presentatio…
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Top challenges in recombinant protein purification process development
First of all, why can process development be much more complex for recombinant proteins compared to traditional monoclonal antibodies?
Emma Lind: Yes. Well, for recombinant proteins, you often don…
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Optimizing your Cell Culture Process to Improve Productivity
… work with biopharma companies that are producing therapeutic proteins, biosimilars, and monoclonal antibodies. This service is useful for smaller companies with limited resources. These companies ca…
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What’s in your media? How costly is variability of cell culture media to your manufacturing process?
There have been numerous studies which have been done looking at trace metal effects on monoclonal antibodies. Some of the studies performed investigated the glycosylation patterns. For example, the s…
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Working With Advanced Therapeutics: You Bring the Idea, We Bring the Map
Plasmids. mRNA. Oligos. Cell and gene therapies. Antibody variants. Vaccines. We all know these advanced therapies hold huge potential. But developing them isn’t straightforward, and fai…
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Alkaline stability of Fc and VH3 binding in protein A resins
In the development of antibody purification protocols, you need to know your Ab molecule and its possible affinity binding sites for the chromatography resins. In this study, we have looked at…
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Enhancing Resins Addresses Purification Concerns
Existing challenges
Beyond vaccines, biotherapeutic development is seeing the emergence of a variety of other complex modalities, such as bispecific antibodies and protein fragments in addition …
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Maximum Output Starts with Optimized Upstream Processing
Significant growth in the development and manufacturing of biologics—from traditional recombinant proteins and monoclonal antibodies (mAbs) to advanced multispecifics, antibody-drug conjugates, viral …