Search results for "antibodies" in Articles / App Notes
Article
Leveraging Computational Models of Glycosylation for Biopharma QA
…high-mannose glycans, in particular, the five-mannose glycan (Man5), reduces the serum half-life of antibodies (7). Man5 may also enhance antibody-dependent cellular cytotoxicity (ADCC) (8), a mechan…
Article
Are You in Control of the Quality of Your mAbs?
Stuart Knowling from Antibody Analytics presented how the latest innovation in surface plasmon resonance (SPR) technology has been adopted to develop and qualify assays for monoclonal antibodies (mAbs…
Article
Impurity Testing of Biologic Drug Products
Some impurities (especially host cell proteins) may add an immune-stimulating or adjuvant behavior to the therapeutic, causing the patient to generate antibodies or cell-mediated immunity against the …
Article
3rd BioProcessing Asia Preview: Q&A with John Curling
The program always covers the entire biopharmaceutical spectrum from antibodies and blood plasma products to vaccines as well as biosimilars development. BioProcessing Asia also differentiates itself …
Article
Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
…ly-defined, animal-component-free processes that have now become standard for producing recombinant antibodies, therapeutic proteins, and some vaccines. Although the same concerns for safety are ulti…
Article
Detecting Protein Aggregates and Evaluating their Immunogenicity
Mar 01, 2015
By Randi Hernandez
BioPharm International
Volume 3, Issue 28
Aggregation in biopharmaceuticals remains a major concern and threatens the stability of a product. Protein …
Article
The Bullish Outlook for Biosimilars
Kuick Research, Global Cancer Monoclonal Antibodies Market & Pipeline Insight (October 2014).
11. Research and Markets, Global Biosimilars Market Regulations & Pipeline Insight (September 2014).
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Article
What Drove Biopharma Development in 2014?
To that end, PDF articles and posters related to monoclonal antibodies (mAb) were well received by website visitors. In fact, the monoclonal antibody market represents the fastest growing segment with…
Article
Optimizing Resin Performance with Disposable Chromatography Solutions
Tingley (Repligen): Resin structure is central to separation success, especially with more complex proteins such as monoclonal antibodies. OPUS was designed to allow biopharmaceutical manufacturers to…
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Biopharma Manufacturers Respond to Ebola Crisis
Most discussed is the ZMapp cocktail of three monoclonal antibodies from Mapp Biopharmaceutical of San Diego, which made headlines when two American health workers infected by Ebola recovered followin…