Search results for " activity"
Article
Bioburden Control in the Biopharmaceutical Industry
Human activity and normal tasks performed within a manufacturing facility may influence the other contributing factors significantly.
Bioburden contamination is affected by the degre…
Article
Contract Manufacturing Through the Years
The robust environment for contract drug development has fed a frenzy of merger and acquisition activity in the CMO industry as new investors look to break into the industry and current participants l…
Article
Immediate, Flexible Capacity with Hydrated Buffers and Process Liquids
Historically, bioprocessing facilities have prepared buffers and process liquids in-house as a core activity. However, trends suggested buffer fluid preparation is one area seeing increase activity in…
Article
Downstream Processing Continues to Worry CMOs
CMOs are working hard to improve performance by investigating new technologies for filtration and purification.
By Eric S. Langer
Downstream processing continues to be a significant pain poi…
Article
Platform Approach Speeds Process Development
A modular cell-culture platform demonstrates accelerated process development.
By Harald Bradl, Jan Bechmann, Benedikt Greulich, Markus Michael Mueller, Patrick Schulz, Thomas Wucherpfennig
C…
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Framing Biopharma Success in 2016
Framing the 2016 agenda
Early indications are for mergers and acquisitions activity to continue in 2016, and prospects for new drug approvals also are strong. FDA has a busy agenda of legislative …
Article
Tools for Continuous Bioprocessing Development
Could perfusion microbioreactors bring more agility to biomanufacturing?
By Rajeev J. Ram
In semiconductor manufacturing, for example, a thorough understanding of process variation allows co…
Article
Biacore Concentration and Ligand-Binding Analyses
During development and in quality control, a range of analytical technologies are used to characterize biotherapeutic drugs in terms of their structural integrity and activity. In this white
paper, …
Article
Implications of Cell Culture Conditions on Protein Glycosylation
Glycosylation can potentially affect a protein’s half-life, immunogenicity, binding activity, and stability. It is a complex process that consists of the attachment of carbohydrate moieties, with poss…
Article
Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
Optimization of each phase in a chromatographic cycle has a positive impact on productivity.
By Anna Grönberg
An important area of focus for the biopharma industry is the elucidation and dev…