Search results for " therapeutic"
Article
Technology Innovations Improve Process Chromatography Performance
“The other goal, flexibility, is of particular importance for novel therapeutics. Bispecific antibodies, antibody-drug conjugates, engineered glycovariants, fusion proteins—all these molecules need to…
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Cytiva Upgrades Massachusetts Contract Biomanufacturing Site with Increased Capacity and Automation Technologies
Biotechnology companies looking for assistance in bringing therapeutics to market faster can leverage the extensive technical support and single-use biomanufacturing expertise available at this enhanc…
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The Future of Biopharma
In this article, Günter Jagschies, former Senior Director, Strategic Consumer Relations at Cytiva, highlights the evolution of the biopharma industry. Günter discuss challenges and opportunities for…
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
Increased productivity and capacity are especially important for therapeutic areas with a shortage of supply, such as viral vectors, and new advanced therapies such as allogeneic chimeric antigen rece…
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Epitope Binning: A Critical Step in Antibody Selection
Read about how surface plasmon resonance (SPR) is used to characterize closely related “bins” of monoclonal antibodies (mAbs) targeting the same epitope of the target protein, and how the selection …
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Mapping a Route for Cell and Gene Therapy Process Development
The ability to generate and manufacture well-characterized batches of cells for therapeutic use requires significantly different approaches to typically implemented laboratory-based cell-culture techn…
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Driving Improved Access to Biosimilars
FDA, Draft Guidance for Industry: Development of Therapeutic Protein Biosimilars: Comparative Analytical Assessment and Other Quality Related Assessments (Rockville, MD, May, 2019).
13. Z. Brenn…
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Methods Accelerate Biosimilar Analysis
FDA, Draft Guidance to Industry; Development of Therapeutic Protein Biosimilars: Comparative Analytical Assessment and Other Quality-Related Considerations (Rockville, MD, May 2019).
2. R. S Rog…
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Getting it Right from the Start in the Drug Development Process
As a result, the desired therapeutic outcome is achieved without compromising patient safety or introducing dangerous side effects.
Both upstream processing and downstream processing can affec…
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Case Study: Oncolytic Adenovirus Production
Oncolytic viruses constitute a promising therapeutic approach for treatment of cancer. These viruses selectively replicate in tumor cells and effectively kill these cells without harming normal cell…