Search results for "bioreactor" in Articles / App Notes
Article
Continuous Processing for the Production of Biopharmaceuticals
The whole assembly had the capacity to produce end-to-end continuous production from bioreactor to the polished product (Figure 2). The key distinguishing features of this facility were uninterrupted …
Article
Adherent Cell Culture in Biopharmaceutical Applications: The Cell-Detachment Challenge
…e ongoing efforts of the authors to incorporate plasmonic cell-detachment features into the Bolt-on bioreactor (20). Refinement of the methods that have great potential for enabling efficient cell de…
Article
Biopharma in 2015: A Year for Approvals and Innovations
… of a monoclonal antibody
Highly efficient inoculum propagation in perfusion culture using WAVE Bioreactor™ systems
The Use of Dynamic Control in Periodic Counter-Current Chromatography
Pur…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
Equipment Evolves
In the bioreactor area, there is great interest in moving from 2-D to 3-D processing to enable the processing of the cell volumes required, something that companies such as Israe…
Article
Biopharma Advances Demand Specialized Expertise
Single-use disposable bioreactors and similar single-use bioprocess equipment minimize plant downtime, which is traditionally required for line clearance and product changeover. The complexity of prod…
Article
Continuous Chromatography: Trends, Definitions and Approaches
Obviously, prevention of bioreactor contamination is of paramount importance if the reactor is operated in perfusion mode and is connected to a continuous chromatography system, but this can be realiz…
Article
Technologies and Practices Must Evolve to Meet Demand
Cell-culture products, bioreactors, filtration, chromatography columns, and centrifugation received “excellent” grades from more than 24% of those surveyed. More than 10% of the respondents, however, …
Article
Optimizing Resin Performance with Disposable Chromatography Solutions
We are definitely seeing growth as well as demand for larger columns that are suitable for use with 1000-L and 2000-L bioreactors. In just a couple of years this line is generating multimillion dollar…
Article
Single-Use and Continuous Processing Technologies Change Facility Design
With no waiting for cell growth and cell-culture bioreactors continuously operating, columns can be smaller than when they need to handle whole fermenter volumes at one time. Ultimately, the whole fac…
Article
2014 Manufacturing Trends and Outlook
Regulatory issues, costs, analytics, and inadequate bioreactor volumes were other challenges (see Table I).
Process analytical technologies
More than half of the responden…