Search results for "bioreactor" in Articles / App Notes
Article
Intensifying your fed-batch process using cryobags
We will show that high-density cryobags can be used to seed a bioreactor at a 500-fold higher seed density, reducing the total process time by up to 9 days.
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Article
Improving Productivity During Process Development and Scaling of Your Process
…ger processes and challenges to consider
5:17 - Strategies and tools to consider for scaling to bioreactors
6:57 - Important recommendations for developing new processes
Article
Explore the Process Intensifier App
Explore alternatives to intensify your processes >>
How do you know if an intensification approach will give you advantages over your current biomanufacturing process, and how do you choose the …
Article
Cell-free Expression Systems Pose Cell Culture Alternative
Limitations also include expensive centralized facilities, which are needed for good manufacturing practice (GMP); limited volumetric productivities due to the need to propagate cells in batch-mode bi…
Article
Perfusion N-1 – A Way to Improve the Fed-Batch Production Process
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In this article, we show how the conventional N-1 seed train step was replaced by a high-density perfusion and how the production bioreactor can be seeded at a 10-fol…
Article
Simplifying Cell Culture Expansion
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Controlled perfusion in a closed, single-use bioreactor can cut the complexity from your cell culture expansion process, making it possible to go from seed trai…
Article
Technology Innovations Improve Process Chromatography Performance
…se technologies, better characterization of raw materials, and the use of more precisely controlled bioreactors, improvements in downstream processing have not kept pace, says Nandu Deorkar, vice-pre…
Article
Fortem: One Film for Single-Use Bioprocessing
Single-use bags can now be found at every stage of bioprocessing: bioreactor and mixing systems, harvest and collection, purification, and liquid and powder storage and transportation. Thus, Cytiva ha…
Article
Automating the Biomanufacturing Process
One supplier has extended and improved its sensor portfolio, by, for example, including a sensor that measures biomass in the United States Pharmacopeia bags used for rocking motion-based bioreactors …
Article
Reducing Cross-Contamination Risks in Process Chromatography
Today, single-use bioreactors are widely used for biologic drug manufacturing, and downstream disposable technologies for commercial-scale production operations are being introduced and increasingly a…