Search results for "virus"
Article
rAAV Production Using HEK293 Cell Line and Transfection Medium
Improving the performance of a scalable AAV process in Xcellerex™ XDR-10 and XDR-200 bioreactor using HyClone™ peak expression medium.
LEARN MORE >>
Article
Webcast: Repeatable, automated SPR titer assay for adeno- and adeno-associated viruses in crude samples
Fredrik Sundberg at Cytiva shares our recent SPR assay developments for measuring adenovirus and adeno-associated virus titers.
WATCH NOW >>
Article
Enhancing Resins Addresses Purification Concerns
What COVID-19 brings to the table
The COVID-19 vaccines comprise several possible and different modalities, such as messenger RNA (mRNA), attenuated viruses, viral vectors, proteins, and virus l…
Article
Successful Development of Scalable AAV Processes: Part 2 of 2
Watch the Q&A interview >>
In the second of a two-part series, Anki Magnusson, Staff Research Engineer, Protein and Viral Production, and Åsa Hagner-McWhirter, PhD, Senior Scientist, Bio…
Article
Top Challenges to Overcome When Developing AAV Processes: Part 1 of 2
Watch the Q&A interview >>
In the first of a two-part series, Anki Magnusson, Staff Research Engineer, Protein and Viral Production, and Åsa Hagner-McWhirter, PhD, Senior Scientist…
Article
Next Generation Bioprocesses: Mapping Roads to the Future
In downstream processing, it can be intensified capture, in-line virus inactivation, flow through polishing, in-line virus filtration, or single-pass filtration.
Click here to read the article.
Article
Case Study: Oncolytic Adenovirus Production
These viruses selectively replicate in tumor cells and effectively kill these cells without harming normal cells. Selectively engineered, the virus not only destructs the target tumor cell, but also s…
Article
Manufacturing of Viral Vectors
Viruses are infectious agents that can only replicate inside of living cells. This trait is used by molecular biologists for the delivery of genetic materials into cells. Viral vectors are also explor…
Article
Optimization of Adenovirus Midstream Purification Steps
In this application note, studies of midstream purification steps in an adenovirus production process is performed. Based on the results, suggestions for the choice of consumables and conditions for v…
Poster
Adenovirus production in a single-use stirring tank bioreactor system
Scalable and cost-efficient production technologies are needed to enable manufacturing of safe and efficacious clinical-grade virus. Anchorage-dependent cells cultured in roller bottles or cell factor…