Search results for " optimization" in Articles / App Notes
Article
Updating Viral Clearance for New Biologic Modalities
Viral clearance processes and guidance must evolve along with newer biotherapeutic modalities.
By Feliza Mirasol
Ensuring viral clearance (i.e., removal) in downstream purification has becom…
Article
Improving Upstream Predictability
“Process optimization will run towards maintaining cell densities of over 150 million cells/mL and cultivation run times of over 90 days,” he says.
These trends will also drive improveme…
Article
Best Practices for Data Integrity
Forward thinking-manufacturers use these data for business optimization efforts.
Using data to optimize processes
BioPharm: What are some examples of business enabling or optimization…
Article
Tools for Continuous Bioprocessing Development
The device can use up to 324 cultures simultaneously, allowing it to be used for process optimization, screening, and media optimization (14, 15).
• Most recently, Sartorius Stedim’s TAP ambr 15 an…
Article
Use of Multivariate Data Analysis in Bioprocessing
Singh
BioPharm International
The ever increasing demand of biotherapeutics, together with the pressure to contain healthcare costs have motivated biotech manufacturers to focus on process opti…
Article
Fermentation for the Future
Improving efficiency, value chain, quality, and protein complexity with advanced bioprocess development.
Jan 01, 2015
By Cynthia Challener, PhD
Microorganisms—bacteria and yeast—have b…
Article
Challenges in Analytical Method Development and Validation
Obviously, whenever new test methods are to be used throughout product development, more focus should be on the development, optimization, and validation of these new methods.
Guo (FDU): As in …
Article
Design of Experiments for Analytical Method Development and Validation
Textbook approaches to DOE generally suggest a sequential approach to DOE: screening studies, characterization studies, and optimization of the method or process. This approach applied to analytical m…
Article
The Development and Application of a Monoclonal Antibody Purification Platform
A purification scheme to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies.
The following ar…
Article
Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
Further optimization of the process is necessary prior to use in vaccine manufacturing.
References
1. Global Action Plan for Influenza Vaccines (GAP). World Health Organization, Geneva.
…