Search results for " optimization" in Articles / App Notes

Article Framing Biopharma Success in 2016
Corporate restructurings, regulatory initiatives, and biosimilars will shape biopharma development in 2016. By Rita C. Peters The US biopharmaceutical industry turned a new page in 2015 when…

Article Going Small to Achieve Success on the Commercial Scale
… for characterization, efficacy, safety, and other studies, scale-down models are intended to aid in optimization and characterization of the process that will be implemented for manufacture of large…

Article Implications of Cell Culture Conditions on Protein Glycosylation
The authors present a review of the techniques commonly used for glycosylation analysis. By Michiel E. Ultee, PhD, Dr. Richard Easton This article reviews the implications of cell-culture co…

Article CMOs Continue to Improve Overall Biomanufacturing Performance
Better process development is creating industry benchmarks for bioprocessing. By Eric Langer Biomanufacturing efficiency is on everyone’s minds, being the single most important area of focus…

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Surface plasmon resonance is helping define bispecific antibodies, the next-generation of biopharma therapeutics. By Robert Karlsson Abstract Biotherapeutic antibodies are still the larg…

Article Fluid Handling in Biopharma Facilities
Industry experts discuss challenges, trends, and innovations in fluid handling. By Susan Haigney Contamination prevention in biopharmaceutical manufacturing is crucial, and the proper handling…

Article A Q&A With Prof. Alois Jungbauer: The Role of HIC in Biotech
Process Development Forum speaks with Professor Alois Jungbauer, Department of Biotechnology, BOKU, Vienna, about Hydrophobic Interaction Chromatography (HIC). What is your view of HIC in the bi…

Article Quality Systems Key to Lifecycle Drug Management
Jun 01, 2015 By Jill Wechsler BioPharm International Volume 28, Issue 6 The submission and review of manufacturing supplements is costly and time consuming for biopharmaceutical comp…

Article Re-use of Protein A Resin: Fouling and Economics
Mar 01, 2015 By Anurag S. Rathore, Mili Pathak, Guijun Ma, Daniel G. Bracewell BioPharm International Volume 3, Issue 28 In the past two decades, Protein A affinity chromatography ha…

Article Continuous Manufacturing: A Changing Processing Paradigm
Apr 01, 2015 By Randi Hernandez BioPharm International Volume 28, Issue 4 Although continuous manufacturing is well established for bulk chemicals, complex automation and validation …

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