Search results for " cell"
Article
Purification of Plasmid DNA
Plasmid DNA is the building block of advanced therapies. As these therapies take off, so does manufacturing demand. By switching to modern chromatography resins, Cobra Biologics was able to increase…
Article
Securing Today’s Biomanufacturing Supply Chain Using Transformative Supply
Though monoclonal antibodies are expected to continue dominating the market, a more diversified pipeline that includes, for example, DNA and RNA molecules and cell and gene therapies, is anticipated a…
Article
Process Development and Optimization Using the ReadyToProcess WAVE™ 25 Bioreactor System in Dual Mode
Download this application note to learn about the technical feasibility of the Method editor and operations in dual mode (where two parallel cultures are controlled independently) are demonstrated. …
Article
Biosimilar Quality Requirements
Because protein products are, by their nature, complex molecules that are manufactured in living cells and later on purified through a variety of technologies, they will naturally have inherent lot-to…
Poster
Comparison of Three Different Screening Techniques for Predicting Step Elution Conditions for a Cation Exchanger
The aim of this study was to investigate conditions for reduction of host cell proteins (HCP) on a strong cation exchanger, Capto™ S ImpAct. Three different screening techniques using PreDictor™ plate…
Article
Next Generation Bioprocesses: Mapping Roads to the Future
So what are next-generation processes?
These processes overarch the whole manufacturing chain—from cell to molecule and upstream to downstream. They include semi-continuous and continuous approach…
Article
Cytiva and NIBRT Join Forces to Boost Talent Growth in Single-Use Bioprocessing
Cytiva and the National Institute of Bioprocessing Research and Training (NIBRT) in Dublin, Ireland, are combining their expertise to deliver educational programming on biopharmaceutical and cell th…
Article
Monitoring and Control of Inline Dilution Processes
Challener
Process intensification is a major focus of the biopharma industry, with most efforts targeting upstream cell culture and associated processes. Buffer management has received les…
Article
Faster Flavivirus Vaccine Production
The approach helps determine which components in the media will have the most beneficial effect on cell growth. Surface Plasmon Resonance (SPR) analysis during process development provides data about …
Article
Scale-Up Model of a mAb Process from Microbioreactor to XDR-1000
All investigated bioreactor systems displayed similar trends over time and acceptable variability between cultures for viable cell density and viability profile, product titer, lactate, and product qu…