Search results for " cell"
Article
Manage HCPs and Enhance Your Route to Market
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Host cell protein (HCP) management is critical to biologics development—and getting it wrong could delay your development cycle. Learn how the right HCP strategy can enhance…
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The Importance of Process Intensification and PAT for Achieving Real-Time Release
There are some sensors currently used to monitor different parameters of cell-culture processes in near real-time, such as pH, turbidity, dissolved oxygen, carbon dioxide production, key metabolite pr…
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Process Development: 2020 Reflections and 2021 Possibilities
…ck Lab-Scale Columns
Gene Therapies Push Viral Vector Production
Mapping a Route for Cell and Gene Therapy Process Development
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Strategizing for Rapid Changeovers in Biologics Manufacturing
Olivier Le Moal/Stock.Adobe.com
By Cynthia A. Challener
Facility and equipment design are important, but the team and its experience matter most.
Through its Operation Warp Speed pro…
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Towards a Better Process Outcome
Considerations for improving outcome in biopharmaceutical process development.
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The Importance of Partnering for Bioanalytical Studies
Perhaps you have a novel cell therapy, and a flow cytometer is used to collect ‘cellular kinetics’. This means special handling instructions to analyze the samples within the demonstrated stability wi…
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Improving Lentiviral Vector Downstream Processing Workflows
Lentiviral vectors (LVV) are a common vehicle to deliver genetic material in chimeric antigen receptor (CAR) T-cell therapy and gene therapy applications. Production methods have been developed by a…
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The Future of Biopharma
Günter discuss challenges and opportunities for developing and manufacturing drugs based on cell and gene therapy to treat the symptoms of certain diseases—or even cure diseases completely—as well as …
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The Evolution of Supply Chain Security: Increasing Focus on Raw Material Variability
An increase in the development of biological and patient-specific drugs has also reinforced the demand for heightened raw material control.
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
The requirement for greater oxygen transfer in high-density cultures and minimal shear stress on delicate cells pose technical challenges for single-use bioreactor design, and vendors are responding w…