Search results for " recombinant" in Articles / App Notes
Article
Re-use of Protein A Resin: Fouling and Economics
Mar 01, 2015
By Anurag S. Rathore, Mili Pathak, Guijun Ma, Daniel G. Bracewell
BioPharm International
Volume 3, Issue 28
In the past two decades, Protein A affinity chromatography ha…
Article
Ligand-Binding Assays and the Determination of Biosimilarity
Therefore, the company immobilized all six recombinant Fc receptors on nickel-coated biosensor tips for use in BLI analyses. “With this approach to binding kinetic analysis, the KD values for mAbs, bo…
Article
Viral Clearance Challenges in Bioprocessing
…ice/porcine parvovirus [MVM/PPV]) is applied for the viral clearance validation of cell line-derived recombinant products. The achieved single reduction factors are summed up to an overall reduction …
Article
Setting Standards for Biotech Therapeutics in India
Approval of the first recombinant DNA product, human insulin, occurred only in 1982. The experience is even more limited in India. The government, through agencies such as the Department of Biotechnol…
Article
Challenges of Protein Aggregation During Purification
…itor inclusion body solubilization, protein refolding, and aggregation near the production line of a recombinant protein-based vaccine candidate (1). Use of such real-time process analytical techniqu…
Article
Q&As with Industry Leaders
…Liderfelt, Global Product Manager, Monoclonal Antibody Polishing, Cytiva
Top challenges in recombinant protein purification process development
Jeanne Linke Northrop, BioPharm Intern…
Article
Trends in BioPharma Approvals in 2013
In 2013, 20 products containing new biopharmaceutical molecular entities (defined herein as recombinant proteins, monoclonal antibody or biosynthesized nucleic acid-based products) were approved in t…
Article
The Development and Application of a Monoclonal Antibody Purification Platform
We measured residual recombinant protein A levels using a sandwich ELISA kit from Repligen (Waltham, MA). Finally, residual total DNA was evaluated by extraction using the DNA extractor kit from Wako …