Search results for " monoclonal"
Article
Establishing a Robust Workflow to Identify High-Performing GOCHO™ Clones
Our cell line development platform uses the GOCHO™ host cell line to minimize the risk and timeline to develop high-performing clones suitable for manufacturing.
LEARN MORE >>
Article
Scaling a mAb production process to Xcellerex bioreactors
Moving a monoclonal antibody production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
READ MORE >>
Article
Trends in Outsourcing of Bioprocess Development
Growing numbers of conventional recombinant proteins and monoclonal antibodies, as well as next-generation molecules such as multispecifics, antibody-drug conjugates, and cell and gene therapies, are …
Article
Top Process Development Trends for 2021 and a Look into 2022
According to Peggy Lio, senior director of global cell culture services at Cytiva, over the past 20 years, there has been a significant increase in titers of bioprocess, especially for monoclonal anti…
Article
Maximum Output Starts with Optimized Upstream Processing
Significant growth in the development and manufacturing of biologics—from traditional recombinant proteins and monoclonal antibodies (mAbs) to advanced multispecifics, antibody-drug conjugates, viral …
Article
Cell Culture Media Selection Guide for Your Lab Wall!
Yes, send me a poster >>
Doing cell culture and upstream process development on antibodies, vaccines, or viruses? Then you’ll want this poster. It will help you select the right cell culture medi…
Article
Antibody Production Workflow
Explore the workflow here >>
Antibody-based therapies have evolved beyond monoclonal antibodies (mAbs) to include bispecific antibodies, antibody fragments, antibody-drug conjugates (ADCs), and m…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
“Many of these technologies have been designed in the context of monoclonal antibody production, which is based on suspension platforms, so the adoption of existing PAT for viral-vector production wil…
Article
Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
The rise of therapeutic monoclonal antibodies (mAbs) in the 1980s drove the requirement to adapt Chinese hamster ovary (CHO) cells to suspension in order to allow the use of stirred tank bioreactor fo…
Article
Setting Up Bioprocessing Systems for Digital Transformation
Digitalization of bioprocessing operations, equipment, and facilities can improve workflow and output, but maintaining data integrity is a concern.
By Feliza Mirasol
The advancement of digit…