Search results for " monoclonal"
Article
Get Started: Purification of mAb Variants - eLearning
The success of monoclonal antibodies (mAbs) as therapeutics and the multi-domain structure of antibodies has made it possible to create antibody variants, such as bispecific antibodies (bsAbs)…
Article
As the therapeutic pipeline diversifies, chromatography toolboxes are expanding.
Development beyond traditional monoclonal antibodies (mAbs) is increasing, and today, we see antibody variants like multispecific and bispecific antibodies and antibody fragments. In mAb proc…
Article
A Look into Biologic Scale-Up Strategies
Optimizing cell-culture processes for monoclonal antibody (mAb) production is a key factor in scaling up manufacturing to commercial levels. To maximize cell-culture output, strategy is requir…
Article
Fundamentals of hydrophobic interaction chromatography
…urification of a large range of molecules:
* recombinant proteins and peptides
* monoclonal antibodies (mAbs), bispecific mAbs and antibody-drug conjugates (ADC)
* mRNA
* plasmid
…
Webcast
Accelerating time to market through process innovation
Topics include:
- Developing and scaling up a monoclonal antibody platform
- Next generation upstream process enablers
- Developing continuous processing
- Aseptic filling
Article
Visualize the Xcellerex™ X-platform bioreactors in 3D
Bioreactors are integral to the manufacture of protein-based drugs, especially monoclonal antibodies. Xcellerex™ X-platform bioreactors from Cytiva are designed to meet process needs of today …
Article
Optimization of a two-step purification method for bispecific antibodies
Bispecific antibodies (bsAbs) have gained increasing interest over recent years because they can bind two antigens, offering unique modes of action compared to monoclonal antibodies. New and i…
Article
What is process development?
Biopharma process development comprises the activities that help you create a series of steps to produce a biomolecule – a monoclonal antibody (mAb), recombinant protein, viral vector, or other produc…
Article
Chromatography for the Diversified Antibody Pipeline
…aphy capture that are used in antibody processing?
Eva Helding: The advantage of producing monoclonal antibodies is that we can apply platform processes which makes the development and manu…
Article
Webinar: Establishing a CHO-K1 cell line and cell line development process for biotherapeutics markets
Establishing a robust cell line is a critical step in the development of a biotherapeutic. But how can you meet rapid timelines when the cell line development workflow is challenged by doc…