Search results for "flexible"
Article
A Plastic Pipeline for Commercial Bioprocessing?
…manufacturing services for biologics and features extensive use of single-use technologies uses for flexible cGMP and non-GMP production, the company reports.
The facility features mostly sing…
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Process Chromatography: Continuous Optimization
“This effect can be achieved through the use of so-called tentacles, grafted linear chains presenting the ion exchange functions in a more flexible way that allows multi-point interactions with the pr…
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The New World of Biopharmaceutical Manufacturing
Flexible facilities are likely to become an important part of large biopharma’s production network and allow much needed agility in operations.
Isberg (Entegris): I think the biggest adv…
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Perfusion in the 21st Century
These drugs are often produced in smaller, more flexible facilities that are designed to manufacture multiple products, and often involve the use of disposable equipment. Biosimilars manufacturers are…
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Microbiological Testing: Time is of the Essence
Pressures to accelerate current and next-gen therapies are challenging traditional microbiological testing methods.
By Cynthia A. Challener
Effective microbiological testing during biopharmace…
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Antibody Production in Microbial Hosts
However, recent small-angle X-ray-scattering experimental observations by researchers have suggested that aglycosylated Fc has a more flexible CH2-CH3 interface than previously imagined. This is due t…
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Quality by design for biotechnology products—part 1
Consequently, companies may be able to develop an efficient, cost-effective commercial process for such products, and benefit from a more flexible reporting mechanism for changes to the application af…
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Single-Use Technologies Prove Effective for Viral Vector Process Development
The benefits of single-use technologies for upstream viral-vector processes clearly outweigh their disadvantages.
Cynthia A. Challener
Upstream viral-vector processes can have sig…
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Next Generation Process Chromatography
Chromatography is an essential part in the production of all biopharmaceuticals. Without it the industry would not be able to produce therapeutics in an economic manner. This is true for monoclonal …
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
By establishing effective management of data and knowledge, it will be possible to employ advances, such as artificial intelligence and synthetic biology, to their full potential in upstream bioproc…