Search results for " PrismA"
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Getting Started with Fibro PrismA - Free e-Learning
Fibro PrismA units for rapid cycling chromatography connect to ÄKTA™ systems in the same way. Additionally, you can use the same buffers.
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Evaluation of Fibro PrismA for Scalable Single-Use mAb Purification
Bayer worked with Cytiva to evaluate a fiber-based alternative, Fibro PrismA, to determine its potential as a truly single-use mAb capture technology. The team assessed scalability from lab- to proces…
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Cytiva Advances Fiber Chromatography Technology with New Launch
27, 2021, Cytiva announced the launch of HiScreen Fibro PrismA, the newest product available for early monoclonal antibody (mAb) purification process development. The product complements HiTrap Fibro …
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Process Economy Simulations on a Protein A Capture Step
This application note gives calculation examples that highlight scenarios where the enhanced capacity and alkaline‐stability of MabSelect PrismA can provide process economic benefits to large‐scal…
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Rapid Cycling Protein A-Based Fiber Chromatography to Address Emerging Downstream Bottlenecks
Fibro PrismA is a new protein A fiber chromatography format developed to complement traditional resin-based chromatography. The protein A fiber matrix has an open pore structure in which mass transf…
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Capacity and Performance of a Next Generation Protein A Chromatography Resin
This application note demonstrates the binding capacity and purification performance of MabSelect PrismA in comparison with its predecessor products for both polyclonal and monoclonal antibodies. An i…
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Dynamic Binding Capacity in Fiber-Based Chromatography
Fiber chromatography matrices such as Fibro PrismA can bind a large amount of protein in a fraction of the purification time required for an affinity resin. Just like with resins, the dynamic binding …
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Sanitization Opportunities for Protein A Resins
Here, we describe an approach to safely sanitize our new generation bioprocess protein A affinity resin for antibody purification—MabSelect PrismA—with 30 mM PAA combined with NaOH cleaning-in-place r…
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Developing a Closed, Connected Single-Use mAb Purification Process
In the Protein A step, Fibro PrismA is compared with MabSelect PrismA regarding process time, recovery, and purification performance.
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Speeding Up mAb Purification Using Fiber-based Technology
Read more on high throughput automated mAb purification using HiTrap Fibro PrismA.