Search results for " upstream" in Articles / App Notes
Article
Understanding and Controlling Raw Material Variation in Cell Culture Media
Manage variability through advanced analytical methods and risk-based assessment.
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Article
Cytiva Upgrades Massachusetts Contract Biomanufacturing Site with Increased Capacity and Automation Technologies
Cytiva has completed the extensive renovation of its Fast Trak cGMP contract biomanufacturing and process development site in Marlborough, MA, USA.
The upgraded facility is 60,000 square-feet (5…
Article
Challenge Analytical Complexity: Biacore™ SPR Systems for Candidate Selection, Characterization, and Quality Control
This webinar presents the utility of Biacore™ systems at all stages of the process, from selection of first candidates to clinical lead, as well as how to shorten and streamline the time to results …
Article
Purposeful Design and Development of a Next Gen Single-use Bioprocess Film
Cytiva recognizes the need for a film constructed specifically to meet the complex bioprocessing nature of a multitude of biologics.
Introducing Fortem™ film, a platform film technology built spe…
Article
Rapid Cycling Protein A-Based Fiber Chromatography to Address Emerging Downstream Bottlenecks
Fibro PrismA is a new protein A fiber chromatography format developed to complement traditional resin-based chromatography. The protein A fiber matrix has an open pore structure in which mass transf…
Article
Purposeful Design and Development of a Next-Generation Single-Use Bioprocess Film
Recognizing the need for a film constructed specifically to meet the complex bioprocessing nature of a multitude of biologics, Cytiva has developed Fortem™ film.
Fortem™ is purposefully des…
Article
Evaluation of Hek293 Cell Growth and Adenovirus Productivity in HyClone CDM4HEK293 Medium
This application note demonstrates growth and adenovirus productivity of HEK293 cells and explores the key factors involved in the optimization of cell culture performance and scalability.
Cli…
Article
Scalable ADCF Virus Production Using HyClone™ VaccineXpress Medium
In this study, HyClone VaccineXpress cell culture medium was used for the propagation of influenza virus and rotavirus in an animal-derived component-free (ADCF) process. Small-scale microcarrier cu…
Article
Collaborative PD Outsourcing: Why Closer is Better
Sharing process details externally might seem too close for comfort, but when it comes to process development (PD) outsourcing, a close collaboration can actually bring added benefits.
Cl…
Article
Best Practices for Selecting a Top-Quality Cell Line
Irina Shi - Stock.Adobe.com
Leveraging automation and a step-by-step approach are keys to success.
By Cynthia A. Challener
Cell lines determine the performanc…