Search results for " resin"
Poster
Impact of sporicidal agent on MabSelect SuRe™ protein A resin lifetime
However, many of the protein-based chromatography resins used in purification of biomolecules are sensitive to harsh sanitization conditions. In this application note, the effects of treating MabSelec…
Article
Maximize resin usage with continuous bioprocessing
Periodic counter-current chromatography (PCC) is a multi-step approach to maximize the chromatography resin capacity utilization and minimize process time. The technology employs three or more chromat…
Article
Buffer optimization for separation of bsAb in a capture step using MabSelect™ VL resin
…r bsAb’s, and removal of light chain from mAbs during elution when using MabSelect™ VL protein L resin. The video includes results of these experiments and a discussion of how buffer screening enable…
Article
Process development using a nonaffinity method vs Cytiva™ Protein Select™ resin
The first method is using nonaffinity chromatography steps (AIEX + heat treatment + HIC), while the second method is using the novel affinity Cytiva™ Protein Select™ resin for the capture step, follow…
Article
Selecting Chromatography Resins for Bispecific Antibody Purification
Advances in chromatography resins are helping to simplify downstream operations and improve separation performance.
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Article
What Makes a High-Quality Chromatography Resin?
Learn the process of what makes a high-quality chromatography resin.
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Article
Cytiva Acquires Chromatography Resins Manufacturing Facility in Muskegon, Michigan
Cytiva has acquired a new chromatography resins manufacturing site in the United States as part of its $1.5 billion capacity expansion investment.
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Article
Efficient Sodium Hydroxide Sanitization with a Novel Procedure of AxiChrom™ Columns Packed with Chromatography Resin
Here, we describe a microbial challenge test with a concentration of 1-M NaOH to mimic typical sanitization practices employed by the biopharma industry for a broad range of resins. The final version …
Article
How To Interpret Protein Binding Capacity: Chromatography Resins
The comparison between protein binding capacities of resin from different suppliers is not always straightforward. Different methods may have to be used, and often these methods are not stated direc…
Article
How to Determine Dynamic Binding Capacity (DBC) of Chromatography Resins
In some cases, you might need to determine the DBC yourself to screen for the best resin and running conditions for your specific protein.