Search results for " Xcellerex"
Article
Stirring up the fermentation game
The Xcellerex XDR-50 MO fermentor system is purpose-designed and built to overcome the mammalian single-use system limitations in fulfilling these needs (Fig 1).
Article
Designing a 1.5 L Bench-Scale Model of a Perfusion Process
Establishing an appropriate model allows for higher throughput during simultaneous operation and monitoring of several cultures at different process conditions. In this article, we discus…
Poster
Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
…rum-free cultivation medium using spinners, WAVE Bioreactor™ 20/50, ReadyToProcess WAVE™ 25, and Xcellerex™ XDR-10 single-use bioreactor systems. Cells in each WAVE Bioreactor system were infected wi…
Article
rAAV Production Using HEK293 Cell Line and Transfection Medium
Improving the performance of a scalable AAV process in Xcellerex™ XDR-10 and XDR-200 bioreactor using HyClone™ peak expression medium.
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Article
Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
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This article summarizes the results of Escherichia coli growth performance for plasmid production in a 5 L glass fermentor, which was scaled up to 80 and 160 L scale in Xcellerex™ X…
Article
Accelerating an Orphan Therapy to Market
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This case study shares the work of Cytiva’s Fast Trak Services team to help accelerate development of a process for cGMP production of material for toxicology studies.…
Article
Perfusion N-1 – A Way to Improve the Fed-Batch Production Process
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In this article, we show how the conventional N-1 seed train step was replaced by a high-density perfusion and how the production bioreactor can be seeded at a 10-fol…
Article
Start-to-Finish Connected Manufacturing
That’s why we are demonstrating our mAb process that tested the performance of a new Xcellerex automatic perfusion system (APS) bioreactor, compared resin and fiber-based chromatography, and utilized …
Article
Developing a Continuous Large-Scale Prefusion Cell Culture Process
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Perfusion processes enable continuous operation over extended periods of time by constantly providing fresh nutrients for the cells and simultaneously removing …
Article
Improving Upstream Predictability
… Vermunt, and will soon introduce an automatic perfusion system that integrates into the company’s Xcellerex bioreactor platform to facilitate intensification during both N-1 and N stages. The compan…