Search results for " bioprocess"
Article
Fast Turnaround with Automated Column Packing
To learn more about automated packing and other way to gain efficiency in downstream bioprocesses download the white paper: Unlocking the Potential for Efficiency in Downstream Bioprocesses.
Article
Designing a Biomanufacturing Facility Incorporating Single-Use Technologies
…derived or microbial cell-derived? While these questions are most pertinent for the selection of the bioprocessing technologies required, they are also important for the design of the facility itself…
Article
A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
At the heart of this strategy is the view that the production cell line is the foundation of any bioprocess, and thus, appropriate genetic characterization of the production cell line is absolutely cr…
Article
Antibody Production in Microbial Hosts
Further, mAb production in microbial hosts such as bacterial cells completely abrogates the nuisance of glycosylation control and speeds up production timelines, further simplifying bioprocessing. The…
Article
Biopharma Outsourcing Activities Update
So essentially, this year BioPlan found something of a bimodal trend, more complex process outsourcing and greater outsourcing volume of basic bioprocessing, such as fill-finish, and other activities.…
Article
Evolution of the Monoclonal Antibody Purification Platform
Zarbis-Papastoitsis, BioProcess International (2009).
12. J.Chen et al., J.Chromatogr. A, 1217(2), 216-224 (2010).
13. I.F. Ferreira et al., J.Chromatogr. A, 1195(1-2), 94-100 (2008).
14. …
Article
Under pressure: exploring root causes of leaks in single-use mixers
Equipment failures in large-scale bioprocess can be costly in terms of material loss and downtime. For large manufacturers, a batch failure (i.e., one that causes product loss) can cost millions of do…
Webcast
Webinar: Building an Innovative Integrated Continuous Downstream Manufacturing Platform for the Production of Biologics
Integrated continuous bioprocess (ICB) is a powerful way to achieve that.
A streamlined control strategy for AstraZeneca’s development of ICB to test this implementation for 14 days of continuous …
Article
A Closer Look at Affinity Ligands
The most common example in the realm of bioprocessing is Protein A, which has an extremely high affinity for some immunoglobulin molecules. Other examples include antibody/antigen, enzyme/substrate, a…
Article
What is process development?
Learn more about process development
Get better understanding of definitions, activities, and things to consider when developing an upstream and downstream bioprocess
- Process developme…