Search results for " bioprocess"
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Scaling Up Novel Therapies
“Platforms have had a very positive impact on companies’ ability to develop products and manufacture them less expensively,” says Tom Ransohoff, vice-president and principal consultant with BioProcess…
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QbD Improves Cell-Culture Process Control
However, using a quality-by-design (QbD) approach that employs predictive modeling can improve the quality of end product as well as the efficiency of the bioprocess.
Real-time quality control
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Speed and Flexibility Are Dual Goals for Biopharma Operations
What new technologies and products are impacting bioprocessing operations?
Recent product introductions for bioprocessing operations—such as advances in bioreactor technology, media, buffers, and …
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Improving Process-Scale Chromatography
New resin chemistries
New chromatography resins and chromatography ligands are constantly being developed, according to Lotta Ljungqvist, head of bioprocess R&D for Cytiva. She points to several n…
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Lessons Learned Accelerate Vaccine Development
Early bioprocessing challenges
The diversity of viruses that cause diseases, the number of different vaccine products, and the variety of vaccine production methods all contribute to the complexit…
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Fermentation for the Future
“These inclusion bodies are isolated during bioprocessing. Subsequently, the IBs are solubilized, and in a refolding step, the protein is renatured and afterwards purified. Therefore, production of re…
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Optimizing Resin Performance with Disposable Chromatography Solutions
Shawn Knol/GETTY IMAGES
By: Randi Hernandez
BioPharm International, spoke to Fredrik Lundström, product manager, Cytiva; Jonathan Royce, bioprocess senior product manager of antibody affinity …
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Outsourcing Trends in Biopharmaceutical Manufacturing
The survey found 19 common actions associated with bioprocessing, and five of these were related to outsourcing. These five were near the bottom of the list. But it should be noted that they are growi…
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The Future of Biopharma
Much of this anticipation is driven by pressure for the next new thing, demand for better bioprocessing technologies, and by concerns about weak development pipelines. In response, most large pharmace…
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Addressing the Challenges in Downstream Processing Today and Tomorrow
Technological advances in bioprocessing have led to tremendous increases in product and cell mass that in turn have posed several challenges to downstream process development of mAbs. Novel approaches…