Search results for " laboratory"
Article
Maximum Output Starts with Optimized Upstream Processing
By Cynthia A. Challener
Biopharmaceutical companies and contract manufacturers respond to changing demand dynamics for upstream bioprocessing capacity.
Significant growth in the develo…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
Increasingly, single-use technologies—such as shake flasks, rocking-bioreactor bags, and larger bioreactor bags—have been used for laboratory- to commercial-scale viral vector production, including fo…
Article
Assessing Manufacturing Process Robustness
Amol Galande is senior manager of the process development laboratory at Lupin Pharmaceuticals. Marzena Ingram is senior consultant at Validant. Robert Rhoades is managing partner at Validant.
Article
The Importance of Process Intensification and PAT for Achieving Real-Time Release
Creativity and collaboration are required to overcome complex method development challenges.
By Kelvin H. Lee and Mark Lies
…
Article
Next Generation Process Chromatography
Hardick: The concept for using nanofibers as a chromatography support structure came from a chance meeting of Professor Dan Bracewell at UCL and Professor Bob Stevens at Rutherford Appleton Laboratory…
Article
Can Vaccine Development Be Safely Accelerated?
For its COVID-19 vaccine, the UQ researchers created a first candidate in the laboratory in just three weeks (9). This work confirmed that the engineered vaccine candidate is readily recognized by the…
Article
Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
By establishing effective management of data and knowledge, it will be possible to employ advances, such as artificial intelligence and synthetic biology, to their full potential in upstream bioproc…
Article
Efficient and Scalable Buffer Preparation
It also explains how ÄKTA avant™ can be used to obtain molar recipe information instead of doing tedious and time-consuming titration in the laboratory.
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Article
Best Practices for Selecting a Top-Quality Cell Line
Irina Shi - Stock.Adobe.com
Leveraging automation and a step-by-step approach are keys to success.
By Cynthia A. Challener
Cell lines determine the performanc…
Article
Cell-Culture Advances Test Bioreactor Performance Models
Challener
Modeling and simulation are recognized to provide assistance in predicting bioreactor performance, both for initial laboratory runs and when scaling to the pilot plant and commercial ma…