Search results for " connected"
Article
Moving PAT from Concept to Reality
On-line sensors are connected to process side streams and perform periodic automatic sampling, returning fluid back to the process streams after analysis is complete. At-line—or off-line—analyses invo…
Article
Achieving Process Balance with Perfusion Bioreactors
One way to simplify perfusion processes is to have the cell retention device closely connected to the perfusion bioreactor, yet have the flexibility to operate with multiple commercially available per…
Article
Making the Move to Continuous Chromatography
Continuous chromatography systems are designed to be loaded continuously, which is a useful approach when the purification step is connected to an upstream perfusion bioreactor. There are several diff…
Article
Improving Upstream Predictability
Univercells has leveraged process intensification in a new single-use bioreactor design that features a structured fixed-bed bioreactor connected to an automated tangential flow filtration concentrato…
Article
Integrated Semi-Continuous Process for mAb Production
Examples where two or more unit operations are connected and integrated are, therefore, of great interest for understanding the technical solutions as well as the approach for overall control.
Th…
Poster
Improve operational efficiency in biomanufacturing with comprehensive automation solutions
However, equipment used are often connected only by process; that is, the bioprocess material passing between each of them. Often this connection is discontinuous, meaning equipment is controlled on a…
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Article
Digitalization: The Route to Biopharma 4.0
In periodic counter-current chromatography, sensor data from ultraviolet absorbance connected at the primary load column can be used to control column loading (21).
Advanced control systems …
Article
Track-and-Trace Progress Benefits Supply-Chain Security Efforts
By Agnes Shanley
The industry has made great strides in implementing serialization technologies, while technology developers are enabling more open access to real-time transportation data.
S…
Article
Strategizing for Rapid Changeovers in Biologics Manufacturing
Automation software can provide guidance in ensuring that a single-use flow-path is properly connected, thereby saving time performing manual validation, Shave adds. The software can also generate aut…