Search results for " process"
Resource
Accelerating Process Development with Rapid Cycling Chromatography
June 2nd 16 CEST |10 EDT
Article
Meeting the Process Development Challenges of a Diverse Biologic Pipeline
Click here to read more >>
Understanding the challenges novel and diverse biological molecules can create and how to manage these challenges is key to ensuring they reach patients safely and eff…
Article
Lentiviral Vector Upstream Process in Single-use Bioreactors
Click here to read the article >>
Lentiviruses exhibit many desirable properties as gene transfer vehicles, such as high transduction efficiencies, ability to infect both dividing and nondivi…
Article
Process Development and Optimization Using the ReadyToProcess WAVE™ 25 Bioreactor System in Dual Mode
Download this application note to learn about the technical feasibility of the Method editor and operations in dual mode (where two parallel cultures are controlled independently) are demonstrated. …
Article
Developing an Efficient Adenovirus Downstream Purification Process
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and adenovirus is evaluated as vaccine delivery system in many preclinical and clinical studies…
Poster
Repurposing Fed-Batch Media and Feeds for Highly Productive CHO Cell Perfusion Processes
The authors developed a method for identifying first-generation perfusion culture media based on existing fed-batch media and feeds. Here, they show that they can obtain culture media that successfull…
Article
Automated In-Line Buffer Preparation from Ready-Made Stock Solutions in a mAb Process Step
Buffer preparation is both time-and space-consuming and can easily become a challenge in biomanufacturing. This application note describes a lean approach to buffer preparation by implementing in-li…
Article
Understanding Validation and Technical Transfer, Part 3
When correctly done, linking process to product to patient, validation ensures safe and effective drug and biologic products and benefits the patients whose health and wellbeing depend on them.
…
Article
Understanding Validation and Technical Transfer, Part I
Large-molecule drug products and attendant manufacturing processes often involve complex syntheses and purification steps that differ substantially from those employed for small-molecule pharmaceutica…