Search results for "bioprocessing"
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Scaling Up Novel Therapies
Scaling Up Novel Therapies
Platform processes have improved monoclonal antibody scale-up. Can they do the same for personalized therapies?
By Agnes S…
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QbD Improves Cell-Culture Process Control
…ethodology used for multivariate control in many other process industries, would be best suited for bioprocessing. The goal of MPC is to meet various CQA specifications by manipulating process inputs…
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Speed and Flexibility Are Dual Goals for Biopharma Operations
What new technologies and products are impacting bioprocessing operations?
Recent product introductions for bioprocessing operations—such as advances in bioreactor technology, media, buffers, and …
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Improving Process-Scale Chromatography
In the immediate future, downstream bioprocessing will likely involve hybrid solutions with both single-use and stainless-steel equipment and limited linkage of unit operations.
While there are no…
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Lessons Learned Accelerate Vaccine Development
Early bioprocessing challenges
The diversity of viruses that cause diseases, the number of different vaccine products, and the variety of vaccine production methods all contribute to the complexit…
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Fermentation for the Future
“These inclusion bodies are isolated during bioprocessing. Subsequently, the IBs are solubilized, and in a refolding step, the protein is renatured and afterwards purified. Therefore, production of re…
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Optimizing Resin Performance with Disposable Chromatography Solutions
…nager of antibody affinity media, Cytiva; and Steve Tingley, vice-president of sales and marketing, bioprocessing, Repligen about current trends in disposable chromatography and how the technology wi…
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Outsourcing Trends in Biopharmaceutical Manufacturing
The survey found 19 common actions associated with bioprocessing, and five of these were related to outsourcing. These five were near the bottom of the list. But it should be noted that they are growi…
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The Future of Biopharma
Much of this anticipation is driven by pressure for the next new thing, demand for better bioprocessing technologies, and by concerns about weak development pipelines. In response, most large pharmace…
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Addressing the Challenges in Downstream Processing Today and Tomorrow
Technological advances in bioprocessing have led to tremendous increases in product and cell mass that in turn have posed several challenges to downstream process development of mAbs. Novel approaches…