Search results for "Mab"

Article Top Tips for Successful Development of Antibody Chromatography Processes
Then, he shares his top tips for addressing challenges associated with mAb aggregates removal and separation of homo and heterodimers. New further support from Cytiva? Click here to req…

Article Cytiva Advances Fiber Chromatography Technology with New Launch
27, 2021, Cytiva announced the launch of HiScreen Fibro PrismA, the newest product available for early monoclonal antibody (mAb) purification process development. The product complements HiTrap Fibro …

Article Witnessing Major Growth in Next-Generation Antibodies
Challener Next-generation antibodies are designed to be more specific and are often more potent than traditional monoclonal antibodies (mAbs). As a result, their commercial potential is significan…

Article Trends in BioPharma Approvals in 2013
Hospira’s Inflectra (also approved under a separate marketing authorization as Remsima) is even more interesting in that it represents the first ever biosimilar mAb to gain approval in Europe. It is a…

Article The Development and Application of a Monoclonal Antibody Purification Platform
The following article describes the development of a purification platform for monoclonal antibodies (MAbs) at Pfizer's Global Biologics division, including how the individual unit operations have bee…

Article A Closer Look at Affinity Ligands
Large-scale manufacturing of a therapeutic monoclonal antibody (mAb) starts with the expression of the antibody in mammalian cells, typically CHO [Chinese hamster ovary] cells, followed by a series of…

Article Setting Up Bioprocessing Systems for Digital Transformation
He emphasizes that, in addition to maintaining data integrity as critical information passes across systems, organizations also need to track all the single-use consumables to ensure the right compone…

Article Innovative Chromatography Resins Can Improve Purity and Quality
With ongoing efforts to increase monoclonal antibody (mAb) productivity in large-scale biomanufacturing, biomanufacturers continuously seek advancements in downstream processing technologies, with dow…

Article Single-Use for Downstream Chromatography: Benefit or Hindrance?
In traditional industrial mAb processes, large volumes of both chromatography resin and buffer are required, which translates into high operating expenses. Because chromatography resins make up a larg…

Article Challenges in Cell Harvesting Prompt Enhancements
The higher titers and cell densities made the initial clarification of monoclonal antibody (mAb) product more difficult, driving the need for filtration technologies that can handle the large amounts …

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