Search results for "biopharmaceutical" in Articles / App Notes
Article
Virus-like Particles as Therapeutic Moieties of the Future
In this 44th article in the “Elements of Biopharmaceutical Production” series, the authors review the status of VLPs as therapeutics as well as challenges associated with their analytical and function…
Article
Technology Innovations Improve Process Chromatography Performance
Current challenges
The biopharmaceutical industry continues to face technical and logistical challenges in process chromatography, particularly during scale-up. Although significant work has been …
Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Buffers and salts are typically the largest constituents by volume used in the downstream processing steps for manufacturing most biopharmaceutical products. A typical monoclonal antibody (mAb) proces…
Article
Next Generation Process Chromatography
At the heart of Fibro, we can think of designing your process without the traditional multi-day chromatography steps, and I am sure biopharmaceutical producers will find benefit in Fibro in ways that …
Article
The Need for Advanced Process Modeling for New Therapeutic Biologics
…managing director, Biopharm Services, a UK-based developer of technology solutions and services for biopharmaceutical manufacturing. Sinclair notes that there are specific challenges to some of the n…
Article
Quality by Design in Biotherapeutics Purification: Understanding and Addressing Sources of Process Variability
This white paper summarizes information around resin variability, serving as a reference and providing support for developing robust purification processes for biopharmaceuticals.
Article
Methods Accelerate Biosimilar Analysis
While nIM-MS and, more so, collision-activated IM-MS have gained traction in the past few years in their applicability for analysis of higher structures of biopharmaceutical molecules, HDX–MS has been…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Resin fouling
Another unmet need for biopharmaceutical manufacturers is technology that reduces the cost of resins (3), to allow for greater use of single-use systems to address the resin fouling t…
Article
Cytiva Opens Biotechnology Manufacturing Center in UK
… platform, which has the potential to improve efficiency in the purification steps of manufacturing biopharmaceuticals, gene therapies, and viral vectors. Additional products will also be produced at…
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A Look at the Affinity Chromatography Landscape
With the advent of next-generation biopharmaceuticals, chromatography material suppliers have been challenged to develop affinity ligands and support systems that enable the separation and purificatio…