Search results for " biotechnology"
Article
Adherent Cell Culture in Biopharmaceutical Applications: The Cell-Detachment Challenge
Cell detachment is probably one of the most relevant processes hindering a faster development for cell-based biotechnology. In this article, the authors focus on different strategies available for ani…
Article
Implications of Cell Culture Conditions on Protein Glycosylation
The authors present a review of the techniques commonly used for glycosylation analysis.
By Michiel E. Ultee, PhD, Dr. Richard Easton
This article reviews the implications of cell-culture co…
Article
Changing the Culture of Cell Culture: Applying Best Practices and Authentication to Ensure Scientific Reproducibility
An assessment of mycoplasma contamination in the National Center for Biotechnology Information Sequence Read Archive conservatively found that 11% of projects were contaminated (19). The authors estim…
Article
A Q&A With Prof. Alois Jungbauer: The Role of HIC in Biotech
Process Development Forum speaks with Professor Alois Jungbauer, Department of Biotechnology, BOKU, Vienna, about Hydrophobic Interaction Chromatography (HIC).
What is your view of HIC in the bi…
Article
Breakthrough Drugs Raise Development and Production Challenges
Kay Holcombe, senior vice-president of the Biotechnology Industry Organization, urged close examination of ways to prevent approval delays due to difficulties in making a drug according to specificati…
Article
Risk Assessment and Mitigation in Biopharmaceutical Manufacturing
PDA, Technical Report 54, Implementation of Quality Risk Management for Pharmaceutical and Biotechnology Manufacturing Operations (PDA, 2012).
5. PDA, Technical Report 68, Risk-Based Approach for …
Article
Quality Systems Key to Lifecycle Drug Management
Post-approval changes for biotech therapies will continue to be managed by OPQ’s Office of Biotechnology Products.
A smooth hand-off from new drugs to lifecycle is important, commented ONDP acti…
Article
Host-Cell Protein Measurement and Control
Jun 01, 2015
By Fengqiang Wang, PhD, Daisy Richardson, Mohammed Shameem
BioPharm International
Volume 28, Issue 6, pg 32–38
Host-cell proteins (HCPs) constitute a major part of proce…
Article
A Bright Future for the Plasma Fractionation Industry
That was one of the conclusions reached when the 9th Plasma Product Biotechnology (PPB) meeting ended on the beautiful island of Sardinia, Italy in mid-May. This meeting series, which is a joint organ…
Article
Advanced Technologies Facilitate Scale-up and Technology Transfer
Single-use and modular technologies plus continuous manufacturing are increasingly important to biopharma scale-up and tech transfer.
Jun 01, 2015
By Cynthia A. Challener
BioPharm Inte…