Search results for "downstream" in Articles / App Notes
Article
Rapid Cycling Protein A-Based Fiber Chromatography to Address Emerging Downstream Bottlenecks
Fibro PrismA is a new protein A fiber chromatography format developed to complement traditional resin-based chromatography. The protein A fiber matrix has an open pore structure in which mass transf…
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Selected courses from cell culture and downstream process development to scale-up and manufacturing
Develop your skills and those of your teams with training courses designed for researchers, process development scientists, engineers, and manufacturing operators.
Built upon our expertise…
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Technology Innovations Improve Process Chromatography Performance
By Feliza Mirasol
Selecting an appropriate separation technology for biologic manufacturing is a crucial task in maximizing productivity in downstream bioprocessing. Biomanufacturers consider se…
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Unifying Continuous Biomanufacturing Operations
Downstream continuous purification has seen some success as well, mostly through the integration of various chromatography column sequences. But the continuous production of biologics in a closed, tot…
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Continuous Manufacturing: A Changing Processing Paradigm
…ric Langer, managing partner, BioPlan Associates—are manufactured through perfusion or continuous downstream processing, the field is evolving (1). Most of these processes are done piecewise, however…
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The New World of Biopharmaceutical Manufacturing
Single-use technology has also precipitated changes in upstream and downstream processing.
Pharmaceutical Technology spoke with Eric Langer, managing partner at BioPlan Associates; John …
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Biomanufacturing: Demand for Continuous Bioprocessing Increasing
And continuous processing downstream is still largely lacking and, where implemented, involves just a few of the many unit processes involved in downstream processing. Multi-column, countercurrent, an…
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CMOs Continue to Improve Overall Biomanufacturing Performance
Additionally, 41% reported at least some outsourcing downstream process development activities to some degree. Improvements in process development, therefore, are an encouraging sign for CMOs as this …
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The Challenge of Disruptive Technologies in Bioprocessing
Driving innovation
Drivers behind the development of disruptive downstream technologies include increase in demand for biologics. Demand for mAbs, for example, is expected to increase by one or tw…
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Evaluating the Use of Continuous Chromatography
In downstream processing, continuous chromatography is gaining traction in the purification of protein therapeutics. As the biopharmaceutical industry strives to demonstrate, continuous manufacturing …