Search results for "downstream" in Articles / App Notes
Article
How Do I Fix Asymmetrical Chromatography Peaks?
All good chromatography books say that the peaks in the chromatogram should be symmetrical, but what about real life in the lab? There are many different causes to “fronting” or “tailing” peaks, but…
Article
The Role of CDMOs in Cell and Gene Therapy Process Development
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An experienced contract development and manufacturing organization (CDMO) can ease scaling and tech transfer.
Article
Boost Performance with a Chromatography Resin Update
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As protein purification has evolved and new molecule types have come to the forefront, scientists in process development and biomanufacturing have grown to expect ever-higher…
Article
Biacore™ Analytical Services from Fast Trak™
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Do you need help with your molecular interaction analysis? You can outsource your biophysical screening and characterization assays by working with Cytiva’s Fast Trak…
Article
Effectively Managing Data in Process Development
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Traditional methods for capturing, storing, querying, and managing process development data are time-consuming, prone to error, and can hinder collaboration. Gain a deepe…
Article
Evaluation of Fibro PrismA for Scalable Single-Use mAb Purification
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In clinical monoclonal antibody (mAb) manufacturing, capture on protein A chromatography resin gives excellent recovery and purity. However, because clinical batch siz…
Article
Bind, Cut, Elute — Easy Affinity Tag and Protease Removal
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This blog post discusses automated methods for removing an affinity tag and the protease. The tag is cleaved while the protein is still bound to the affinity re…
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Guide to Polishing Chromatography in Process Development
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This article shares the factors you should consider when developing your polishing steps—from the basics to the typical challenges faced, and how to overcome them.
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Article
Accelerating an Orphan Therapy to Market
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This case study shares the work of Cytiva’s Fast Trak Services team to help accelerate development of a process for cGMP production of material for toxicology studies.…
Article
Diamyd Medical Selects Cytiva’s FlexFactory Platform to Make Precision Medicine Type-1 Diabetes Vaccine
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Diamyd Medical will install a new Cytiva FlexFactory platform in Umeå, Sweden. Once up and running, the clinical-stage biopharmaceutical company will begin manufactu…