Search results for "downstream" in Articles / App Notes
Article
The Development and Application of a Monoclonal Antibody Purification Platform
The goal is to manufacture early-phase material without having to perform downstream development, and the current process as outlined in Figure 1 is capable of meeting that goal. However, further incr…
Article
Flexibility in Biopharmaceutical Manufacturing
Maintaining flexibility in biopharmaceutical manufacturing can deliver positive results.
By: Simon Chalk
BioPharm International
There is a high degree of consensus in the biomanuf…
Article
Free handbook for column packing and maintenance
Does large-scale column packing seem daunting? Impossible to get right? This new handbook can help! Packed with valuable guidance for using AxiChrom™, BPG and Chromaflow™ columns, you’ll disco…
Article
Buffer optimization for separation of bsAb in a capture step using MabSelect™ VL resin
Protein L resins bind to kappa light chain and are often used to purify antibody fragments such as dAbs and Fabs — but they can also be used to remove product-related impurities from bispecif…
Article
Extractables in Single-Use Systems Used in ADC Manufacturing, Part 2
We performed extractables studies on single-use chromatography and tangential flow filtration systems using common solvents in ADC manufacturing, DMA and DMSO. The low levels of extractables f…
Article
Fast Trak™ training and education courses for 2024
Up your game: keep your skills sharp with one of Cytiva's Fast Trak trainings. Dates for 2024 events are live!
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Article
How to put mechanistic modeling into practice
Make it happen! Learn about insider recommendations to get started with in silico process development.
Check out our resources on good modeling practice, case studies, and other publication…
Article
Process Development for Viral Vectors
Scaling viral vector processes can be challenging, but it doesn't have to slow you down. Cytiva can help you own your process and gain valuable expertise. Download a case study from Fast Trak™…
Article
Virus safety challenges: get the job done!
Virus safety is key in bioprocessing. In this free 1-day seminar you’ll learn how to conduct virus filterability trials, including prefiltration.
Click here for more information
Article
Ready for a strong start in oligo manufacturing?
Are you interested in manufacturing your own oligonucleotide therapeutics but don’t know how to start? Or are you already manufacturing your own oligos but are running into challenges? If so, …