Search results for " method"
Article
How to Optimize Protein Desalting
But how do you determine which method to use? And how do you choose the right product for your needs? Learn more in this blog post about using size exclusion chromatography (SEC) for this purpose.
Article
Managing Risk in Raw Material Sourcing
To identify and assess risk, the company uses a documented risk-assessment process, facility audits, and a toolkit that includes such methods as failure modes and effect analysis, fishbone diagrams, a…
Article
Efficient Purification of the Pertussis Antigens Toxin, Filamentous Haemagglutinin, and Pertactin in Chromatography Workflows
The described method resulted in higher purity and yield than what can be expected from a purification process based on salt precipitations and sucrose gradient centrifugation.
Download applicatio…
Article
Improving Process-Scale Chromatography
In-line dilution (ILD) is one method. With ILD, floor space is reduced due to the use of buffer concentrates that are diluted with WFI-grade water as needed.
There are issues with this approach, h…
Article
A Platform Approach to Purification of Antibody Fragments
Antibody fragments constitute a promising class of biopharmaceutical products. As compared with full length antibodies, their fragments have unique properties that make them favorable for certain th…
Poster
Guide to modern BioProcess™ chromatography resins
During method and process development, chromatography resins are selected and tested. In this guide, you can find help to select the resins suitable for your application.
Article
Efforts Accelerate to Streamline Postapproval Change Process
…ease batch size, shift to a new manufacturing facility, or improve process robustness and analytical methods.
Expanded global sourcing and sales complicates lifecycle product management, though, …
Article
Perfusion in the 21st Century
Perfusion support
One of the challenges faced by all companies that are exploring use of perfusion processes is the limited ability to use high-throughput methods in perfusion mode. Currently, the…
Poster
Columns up to 1600 mm in diameter packed with protein A chromatography medium using axial mechanical compression
Different methods have been developed to pack a broad range of chromatography media (resins) in columns with axial mechanical compression. This includes packing of traditional BioProcess™ media, such …
Poster
Residual DNA analysis in influenza vaccine processing
… in DNA concentration from harvest to the final product, which all put strain on the DNA preparation method.
For accurate determination of DNA concentration, recovery is of high importance.…