Search results for " platform" in Articles / App Notes
Article
Diamyd Medical Selects Cytiva’s FlexFactory Platform to Make Precision Medicine Type-1 Diabetes Vaccine
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Diamyd Medical will install a new Cytiva FlexFactory platform in Umeå, Sweden. Once up and running, the clinical-stage biopharmaceutical company will begin manufactu…
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Platform for Purification of VHH-type Antibody Fragments
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Protein A affinity chromatography resins have been used to purify monoclonal antibodies (mAbs) by the bioprocess industry at all scales for a long time. Howev…
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Single-Use Technologies Prove Effective for Viral Vector Process Development
Adherent versus suspension cell culture
As mentioned, viral-vector producers have an initial choice between suspension and adherent production platforms. A key difference between adherent and su…
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Can Vaccine Development Be Safely Accelerated?
Several academic and industrial researchers have also focused on applying novel vaccine development and manufacturing platforms to the accelerated development of a COVID-19 vaccine.
In terms of…
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Addressing the Complex Nature of Downstream Processing with QbD
“In addition, the inherent high risk for drug failure at early stages of development combined with short development timelines suggests the need for a platform approach to manage the early phases of d…
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Emerging Therapies Test Existing Bioanalytical Methods
Platforms for gene- and cell-therapy programs
The choice of platform is primarily driven by and unique to the bioanalytical needs of the gene- and cell-therapy product under development. Specifi…
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Tools for Continuous Bioprocessing Development
• Standardization is hampered by use of various platforms and lack of design rules.
For instance, in cell culture, the typical biopharmaceutical company uses at least a dozen different platforms, …
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Strategizing for Rapid Changeovers in Biologics Manufacturing
…to be a cumbersome and costly process for multiproduct facilities, adds Piergiuseppe Nestola, senior platform technology consultant at Sartorius. “It is not unusual for changeover to require weeks to…
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Best Practices for Selecting a Top-Quality Cell Line
The challenge is to have a cell-line development platform that is robust and flexible enough to allow for troubleshooting across a broad range of production issues,” Fisch concludes.
Added to t…
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Scaling Up Novel Therapies
Used almost exclusively for monoclonal antibodies (mAbs), platforms help shorten development times, particularly early in development, Ransohoff says. They also allow manufacturers to leverage perform…