Search results for " platform"
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Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
This puts mAb purification platforms in a good position to handle future developments in upstream technology. However, although mAbs is still the biggest application area and has significant growth, t…
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Fermentation for the Future
The company is currently implementing an automated microbial mini-fermentation system integrated in a robotic platform. The 15-mL bioreactor is based on single-use technology and allows up to 48 paral…
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A Closer Look at Affinity Ligands
The high specificity and ease of operation of Protein A ligand affinity chromatography has made it the technology of choice and the “darling” of the mAb purification platform process in industry.
Cu…
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Top Tips for Successful Development of Antibody Chromatography Processes
If we look at how the mAbs were purified, it was mostly based on platforms. With the same process or with very small adjustment, you could purify multiple different targets or multiple different targe…
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Enhancing Resins Addresses Purification Concerns
“For some, but not all modalities, platform processes and protocols may be developed enabling a shorter time to market. The mRNA vaccines in particular are still rather new to the market, which is why…
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Cytiva Advances Fiber Chromatography Technology with New Launch
The product complements HiTrap Fibro PrismA, the company’s new fiber-bases Protein A platform launched for research applications in 2020.
The Fibro technology features an open porous adsorbent mat…
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Flexible Facilities for Viral Vector Manufacturing
Cytiva has amassed expertise in modular design and construction with the use of its FlexFactory (a modular end-to-end biomanufacturing platform) as well as its KUBio facility (the FlexFactory inside o…
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
The potential to dramatically increase productivity is a strong incentive: WuXi Biologics has reported a tenfold increase in productivity with their WuXiUP continuous perfusion-based processing platfo…
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Monitoring and Control of Inline Dilution Processes
YMC has partnered with MilliporeSigma to offer a buffer delivery platform launched at INTERPHEX 2019. The integrated solution consists of a buffer dilution system, buffer concentrates, single-us…
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Advances in Engineering of Protein-Based APIs
Recently, more fully human platform technologies have been developed, such as OmniAb (Ligand), Trianni Mouse (Trianni), and huTARG (Innovative Targeting Solutions). “The latter is a fully mammalian te…