Search results for " yield" in Articles / App Notes
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How to program, run and evaluate a design of experiments (DoE)
An application example showcases how to optimize an antibody purification for low dimer-and-aggregate and host cell proteins (HCPs) content while achieving best possible yields.
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Optimizing your Cell Culture Process to Improve Productivity
The information provides a foundation for a robust process with high productivity and consistent yields. Therefore, happy and healthy cells will be the most productive cells.
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What is process development?
Instead, you will switch your focus to making sure you have a robust upstream or downstream process that delivers a high yield and high productivity. Also, your process must be cost-effective and repr…
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From cells to purified capsids: How to develop a scalable rAAV process
The key for a successful process is high overall yields of full capsids with empty capsid reduction and efficient impurity removal.
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A better way to purify small drug volumes
But purifying viral vectors with methods optimized for other products can affect yield, purity, and cross-contamination.
How does the ÄKTA ready™ 450 system tackle those problems?
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Optimization of an antibody polishing step
But what if DoE fails to find robust process conditions? This article shows how to achieve higher yields using mechanistic models to optimize an antibody purification process.
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Enhancing Resins Addresses Purification Concerns
“Although the purification challenges for each modality are different, all downstream processes have the common goal of increasing yields with process efficiency in a cost-effective way while ensuring…
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Single-Use Technologies Prove Effective for Viral Vector Process Development
She also notes that the design of the scale-X bioreactor has been shown to provide significantly higher yields than alternative adherent-cell based systems for virus production, while the inline produ…
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Process Development: Go Smarter, Go Faster! Available on Demand
…he latest techniques and ways of working
• Enhance outcomes: Increase titers and yields while ensuring robust processes
• Overcome obstacles: Address the challenges generated by novel mo…
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Technology Innovations Improve Process Chromatography Performance
Any percentage of improvement in downstream recovery can contribute to improving the ultimate process yield for drug product of the target biologic,” he adds.
Deorkar also notes that there is a la…