Search results for " bioprocesses" in Articles / App Notes

Article Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.   By: Pranav Vengsarkar and Nandu Deorkar I…

Article Cell-Culture Advances Test Bioreactor Performance Models
“While some vendors already offer such sparger technologies, the industry has been slow to update to these sparger technologies, likely due to the revalidation burden of changes to established bioproc…

Article Design Considerations for a Commercial Cell and Gene Therapy Facility
The commercialization of cell and gene therapies has become a reality, prompting deeper considerations of logistics, technology, and design for manufacturing facilities. By Feliza Mirasol …

Article What’s New in Upstream Technologies
Recent upstream processing innovations include enhanced sensor technology, single-use bioreactors, and automated cell culture systems. By Amber Lowry  SCIENCE PHOTO - STOCK.A…

Article Scaling Up Novel Therapies
Scaling Up Novel Therapies Platform processes have improved monoclonal antibody scale-up. Can they do the same for personalized therapies? By Agnes S…

Article QbD Improves Cell-Culture Process Control
al, “Quality by Control: Towards Model Predictive Control of Mammalian Cell Culture Bioprocesses [2],” Biotechnology Journal online, DOI: 10.1002/biot.201600546, March 31, 2017.

Article Speed and Flexibility Are Dual Goals for Biopharma Operations
Bioprocessing facilities, equipment, and materials, as well as strategies to improve biopharmaceutical development and manufacturing, were featured at INTERPHEX 2017, held in March in New York City.…

Article Improving Process-Scale Chromatography
Advances in technology are increasing the productivity and efficiency of commercial-scale chromatography bioprocesses. By Cynthia Challener, PhD Chromatography is a crucial step in the purif…

Article Lessons Learned Accelerate Vaccine Development
Collaboration and single-use technologies aided the rapid scale-up of Ebola vaccine manufacturing. By Cynthia A. Challener Vaccine development is a complicated process that can take many yea…

Article Fermentation for the Future
Improving efficiency, value chain, quality, and protein complexity with advanced bioprocess development. Jan 01, 2015 By Cynthia Challener, PhD Microorganisms—bacteria and yeast—have b…

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