Search results for " bioprocesses"

Article Host-Cell Protein Measurement and Control
Jun 01, 2015 By Fengqiang Wang, PhD, Daisy Richardson, Mohammed Shameem BioPharm International Volume 28, Issue 6, pg 32–38 Host-cell proteins (HCPs) constitute a major part of proce…

Article Technologies and Practices Must Evolve to Meet Demand
Jan 01, 2015  By Rita Peters Through Dec. 3, 2014, nearly 30% of FDA’s new drug approvals for 2014 were for biologic-based therapies, up from 7% in 2013 (1). As the percentage of large-molecule …

Article Raw Material Variability
The biopharmaceutical industry is developing a new approach to controlling variability in raw materials. It would seem that raw materials used in bioprocessing operations are a relatively straig…

Article Innovative Chromatography Resins Can Improve Purity and Quality
By: Feliza Mirasol Recent innovations in chromatography resins offer promising advantages in downstream bioprocessing. With ongoing efforts to increase monoclonal antibody (mAb) productivi…

Article Updating Viral Clearance for New Biologic Modalities
Improvements in his company’s Viresolve Pro product enable viral clearance effectively in both traditional biologics manufacturing as well as in evolving bioprocesses. Ultimately, the effectivenes…

Article Mechanistic Modeling: Current Advantages and Future Opportunities in Biopharmaceutical Process Development
Mechanistic modeling is considered a part of smart process development, which is a collection of approaches to get better process outcomes and speed up process development. This week, Bioproce…

Article Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.   By: Pranav Vengsarkar and Nandu Deorkar I…

Article Cell-Culture Advances Test Bioreactor Performance Models
“While some vendors already offer such sparger technologies, the industry has been slow to update to these sparger technologies, likely due to the revalidation burden of changes to established bioproc…

Article Design Considerations for a Commercial Cell and Gene Therapy Facility
The commercialization of cell and gene therapies has become a reality, prompting deeper considerations of logistics, technology, and design for manufacturing facilities. By Feliza Mirasol …

Article What’s New in Upstream Technologies
Recent upstream processing innovations include enhanced sensor technology, single-use bioreactors, and automated cell culture systems. By Amber Lowry  SCIENCE PHOTO - STOCK.A…

Previous PageNext Page