Search results for " buffers" in Articles / App Notes
Article
Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
One hot article answered two commonly asked questions about in-line buffer preparation, which were “Will our buffers work?” and “How can we be convinced that buffers are made to specification?”
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Article
Driving Change in Biomanufacturing
Whatever the objective, driving change is a challenge. Implementing a new technology into a bioprocess is a big change. The new technology must be fully understood, all regulatory requirements fulfi…
Article
Designing a Biomanufacturing Facility Incorporating Single-Use Technologies
Asking the right questions is crucial to establishing a facility design.
By Peter Genest, John Joseph
The benefits of adopting single-use technologies in the production of biopharmaceuticals…
Article
Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
For our study, these benefits enabled decreased number of buffers needed. The possibility to serially connect Capto Q and Capto Core 700 media columns allows for enhanced system utilization and a redu…
Article
Connected Inline Conditioning for Better Process Efficiency
In this study, we integrated an inline conditioning (IC) system that served as a buffer preparation skid with chromatography and filtration systems. This automated the buffer preparation p…
Article
Get Confident: Inline Conditioning Control Modes
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In this course, you will learn how to use the control modes of the BioProcess Inline Conditioning (IC) system used for buffer preparation. The control modes are the s…
Article
Addressing the Complex Nature of Downstream Processing with QbD
Quality by design brings both challenges and benefits to the development of downstream processes.
By Susan Haigney
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Regulators have been en…
Article
Using Multiple Techniques in Biosimilar Analysis
Application of multiple techniques at different conditions presents a more complete picture of a dynamic situation.
By Rebecca Strawn
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Almost all drug product…
Article
From Darwin to Recombinant Fc Multimers
…n buffer management, which show significant savings in CAPEX, tank space, floor space, and number of buffers when using in-line conditioning to achieve optimized automated approaches. Damien Bataille…
Article
Downstream Processing for Cell-Based Therapies
By Qasim A. Rafiq, Fernanda Masri
With increasing numbers of advanced therapies—including cell and gene therapies—entering early- and late-stage clinical development, significant focus has been …