Search results for " buffers" in Articles / App Notes
Article
Hybrid Bioprocessing: A Q&A with Andrew Sinclair
For support infrastructure as it relates to hold vessels for buffers etc, it is nearly always good to incorporate as much as possible taking account of the practicalities
Continuous bioprocessin…
Article
Unifying Continuous Biomanufacturing Operations
The success of a truly integrated continuous processing platform relies on the collaborative efforts of upstream and downstream specialists.
By Randi Hernandez
When human cells travel throug…
Article
Improvements in Protein A Chromatography
The Protein A step is platformable so that the same buffers and conditions can be used for many different clinical antibody candidates. This allows for fast step development. Alternative technologies …
Article
Speed and Flexibility Are Dual Goals for Biopharma Operations
What new technologies and products are impacting bioprocessing operations?
Recent product introductions for bioprocessing operations—such as advances in bioreactor technology, media, buffers, and …
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
Compared with conventional chromatography, using stainless steel columns, the use of ReadyToProcess Adsorber membranes can help reduce capital investment, consumption of buffers and other process liqu…
Article
Biopharma in 2016: Higher Quality Drugs, Less Expensive Manufacturing
The year ahead is expected to be marked by increased biosimilar development, lower drug prices, and better quality drugs.
The global biopharmaceuticals market was valued at $162 billion in 2014 a…
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How to Optimize Protein Desalting
Most protein purification workflows require desalting, buffer exchange, or both at one or more steps. But how do you determine which method to use? And how do you choose the right product for your n…
Article
Going Small to Achieve Success on the Commercial Scale
Scale-down modeling is instrumental in supporting the development of downstream biopharma manufacturing processes.
By Cynthia A. Challener
Biopharmaceutical manufacturing involves a series o…
Article
Selecting a Comprehensive Bioburden Reduction Plan
Filtration may be used for cell-culture media or buffers. Chromatographic steps, low pH, and chemical inactivation provide virus reduction during processing. Virus and sterile filtration prior to fina…
Article
Using Single-Use Technologies in Downstream Processing
The use of single-use systems in downstream processing offers benefits in filtration and sampling and may reduce the risk of contamination.
Jul 01, 2015
By Susan Haigney
BioPharm Inter…