Search results for " opportunity" in Articles / App Notes
Article
Cell-free Expression Systems Pose Cell Culture Alternative
Cell-free expression is promising in preclinical applications, but still presents challenges to scale up for commercial production.
Feliza Mirasol
Among the challenges in upstrea…
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Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
This article will explore the traditional path from the laboratory to the clinic and how the fixed-bed technology provides an alternative solution to meet commercial demands.
By Alex Chatel and …
Article
WEBCAST ON DEMAND: Accelerate mAb Process Development with Fibro Rapid Cycling Chromatography
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Results in minutes, not hours: That’s one of the ways protein A fiber chromatography opens new opportunities in downstream process development for mAbs. In this webcast, Cytiva e…
Article
Strategies and Emerging Technologies for mAb Capture
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In this webinar, we will describe and evaluate different process intensification strategies for the monoclonal antibody (mAb) capture step. Strategies wi…
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The Importance of Process Intensification and PAT for Achieving Real-Time Release
Creativity and collaboration are required to overcome complex method development challenges.
By Kelvin H. Lee and Mark Lies
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Reimagining Affordable Biosimilars
The advent of biosimilars is an opportunity to address affordability. Development costs have been estimated to be reduced to approximately $50 to $300 million and development time to less than eight y…
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Purifying Samples for Cryo-EM Preps
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Technical improvements in cryogenic electron microscopy (cryo-EM) have triggered a revolution in structural biology and made single-particle cryo-EM …
Article
Strategizing for Rapid Changeovers in Biologics Manufacturing
“This approach affords the opportunity to increase facility throughput,” he says. A phased approach allows for proper and thorough cleaning as the process completes, agrees Husain. In addition, all su…
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Technology Innovations Improve Process Chromatography Performance
This provides an opportunity to increase the number of molecules per facility, Beattie observes. “This goal cannot be achieved without highly productive single-use purification solutions which feature…
Article
Gene Therapies Push Viral Vector Production
The potential opportunity of a vector depends on the type of gene therapy being developed, says Gaurav Chaudhary, CEO of Roots Analysis, a business research and consulting firm. In general, there are …