Search results for "automated"

Article Implications of Cell Culture Conditions on Protein Glycosylation
Such studies require the employment of automated, large-number bioreactor arrays to make the process feasible (2). Special cell-culture considerations for biosimilars Biosimilars are “generic” v…

Article Biopharma Advances Demand Specialized Expertise
With this in mind, substitution of HPLC for UPLC, rapid microbiological screening methods, and investment in automated approaches to complex analytical problems such as protein sequencing are now bein…

Article Continuous Chromatography: Trends, Definitions and Approaches
Process Development Forum speaks with Karol Lacki, Customer Collaborations Leader at Cytiva, about continuous chromatography. There is a lot of attention being paid to continuous chromat…

Article Detecting Protein Aggregates and Evaluating their Immunogenicity
Though DLS does not provide the high resolution of SEC–MALS or FFF–MALS, notes Some, it can be automated via a high-throughput plate reader. To characterize reversible, soluble aggregates that occur a…

Article Optimizing Resin Performance with Disposable Chromatography Solutions
Although the initial uptake of single-use chromatography solutions has been relatively slow, an increased need for higher-capacity resins and the demand for smaller batches has made disposable chrom…

Article Viral Clearance Challenges in Bioprocessing
In these cases, close monitoring of the process, preferably using automated systems, and a good quality assurance/quality control program are essential for preventing such problems, according to Zhou.…

Article DoE Provides Benefits, but Preparation Is Necessary
Nov 1, 2014 By: Cynthia Challener, PhD BioPharm International Volume 11, Issue 27, pp. 28-29  Using a design-of-experiment (DoE) approach allows a formulation development scientist t…

Article Challenges and Trends in Biopharma Facility Design
…dvantage of the benefits of single-use technologies, we offer the FlexFactory, which is a centrally-automated biomanufacturing platform. Philips (Pall Life Sciences): The ‘ballroom’ concept is of…

Article Biopharma Moves to Integrated, Single-Use, Downstream Processing
Suppliers see challenges to the adoption of single-use technologies for downstream processing as opportunities. A lack of single-use technologies The greatest barrier for adoption …

Article Challenges in Analytical Method Development and Validation
Experts give insight on method transfer, QbD, and regulations for analytical method development and validation for biopharmaceuticals. The manufacture of biopharmaceuticals presents …

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