Search results for " protein"
Article
How to Address Bioburden Challenges: Insights and Tips
Another important area where suppliers can contribute is sanitization and storage procedures for protein A chromatography resins, which are widely used to purify mAbs.
Learn more about insights an…
Article
The New World of Biopharmaceutical Manufacturing
Today, we can express proteins in cell culture, so the approach to downstream processing is completely different. In the past five years, the biggest advances have been in the introduction, developmen…
Article
Asked and Answered: Your Questions on Ion-Exchange Chromatography
Check out what questions your fellow protein purifiers have related to ion-exchange chromatography.
The questions are organized in by chief concern, and include buffers, experimental design, L…
Article
Hybrid Bioprocessing: A Q&A with Andrew Sinclair
In the therapeutic protein space, there has not been a truly SU facility at commercial scale.
What could be the main reasons and/or the main drivers that hybrid bioprocessing are being used? Is th…
Poster
Adenovirus production in a single-use stirring tank bioreactor system
Human adenovirus 5 expressing green fluorescent protein (GFP) was used as a model system. By evaluating different cell culture media (CCM) and optimizing the virus propagation in small scale, the proc…
Article
Sources of Bioburden You Might Have Missed
A problem with traditional mAb manufacturing is that there are so many potential entry points for microbial contamination. There are, however, ways to shut the door on contamination.
The risk …
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
Essential Pharmaceuticals provides an animal-component free media that boosts titer and enhances protein quality. It can be difficult to change or improve processes with the strict regulations around …
Article
Single-use Bioreactors Have Reached the Big Time
“[Cytiva] is taking its experience in single-use bioreactor technologies for monoclonal antibody, recombinant protein, and vaccine processes and applying it in our Xuri line of cell therapy equipment …
Poster
Effects of feeding strategy on CHO cell performance in fed-batch cultures
ActiPro cell culture production medium is intended to be used in combination with Cell Boost 7a and 7b supplements to enhance recombinant protein production in fed-batch or perfusion processes. This…
Article
Increase Efficiency in Experimentation with Design of Experiments
Setting up an efficient study can help you save time and allow you to get the most out of screening and optimization experiments during method development. Also, good planning and relevant experimen…