Search results for " antibodies"
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Q&As with Industry Leaders
Discovering the unknown: How does in silico process development change PD scientists’ work?
Jeanne Linke Northrop, BioPharm International
Nora Ketterer, Manager, Modeling Services…
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Evaluating the Use of Continuous Chromatography
Continuous Downstream Bioprocessing for Intensified Manufacture of Biopharmaceuticals and Antibodies. Chemical Engineering Science 2021, 231, 116272. DOI: 10.1016/j.ces.2020.116272
2. Somasun…
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Right the First Time: Bioreactor Scale and Design Translation
Cell culture process transfer requires a good understanding of the physicochemical conditions within a bioreactor. This includes the hydrodynamic environment induced by the agitator and the …
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Pulling Out All the Stops in mAb Manufacturing
While the biopharma industry is pushing the barriers with antibody development, it must also contend with contemporary challenges in bulk monoclonal antibody (mAb) manufacturing. The need for…
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Sign-up to join Chromatography Virtual Summit 2022
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Virtual event 15–17 November 2022
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Cell Culture Media Selection Guide for Your Lab Wall!
Yes, send me a poster >>
Doing cell culture and upstream process development on antibodies, vaccines, or viruses? Then you’ll want this poster. It will help you select the right cell culture medi…
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Cell-free Expression Systems Pose Cell Culture Alternative
Cell-free expression is promising in preclinical applications, but still presents challenges to scale up for commercial production.
Feliza Mirasol
Among the challenges in upstrea…
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Addressing the Complex Nature of Downstream Processing with QbD
When it comes to monoclonal antibodies, MacDonald says that viral clearance processes are “widely known and understood”, with most platforms being developed for effective and orthogonal approaches for…
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Leveraging Computational Models of Glycosylation for Biopharma QA
… high-mannose glycans, in particular, the five-mannose glycan (Man5), reduces the serum half-life of antibodies (7). Man5 may also enhance antibody-dependent cellular cytotoxicity (ADCC) (8), a mecha…
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Are You in Control of the Quality of Your mAbs?
Stuart Knowling from Antibody Analytics presented how the latest innovation in surface plasmon resonance (SPR) technology has been adopted to develop and qualify assays for monoclonal antibodies (mAbs…