Search results for " membranes"
Article
Digitalization: The Route to Biopharma 4.0
These models can capture trends and predict volumetric flow, flux, and pressure across membranes (13).
Implementation of these approaches requires setting up reliable communication protocols an…
Article
Enhancing Resins Addresses Purification Concerns
“Conversely, with production, other methods, such as membranes and monoliths, have been investigated. Although these methods show great promise, further development is still required,” Deorkar says.
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Article
Tips for Purifying and Analyzing Cryo-EM Samples
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Cryogenic electron microscopy (cryo-EM) provides possibilities to determine structures for more challenging proteins, such as membrane proteins and larger protein compl…
Article
Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
A major advantage of SPR-based analysis is its ability to estimate the association and dissociation rate constants, an …
Article
Challenges in Cell Harvesting Prompt Enhancements
…niques: centrifugation, microfiltration, depth filtration, and filtration through absolute pore size membranes (1).
A key challenge in cell harvesting is how to deal with higher cell densiti…
Article
Reducing Cross-Contamination Risks in Process Chromatography
MilliporeSigma, for instance, offers single-use chromatography membranes designed for high mAb throughput that allow the high loadings often obtained in stainless-steel facilities.
Morell…
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Impact of Media Components on CQAs of Monoclonal Antibodies
The authors review how media components modulate the quality of monoclonal antibody products.
By Anurag Rathore, Rajinder Kaur, Dipankar Borgayari
Recombinant protein products have…
Article
Process Chromatography Selection for Downstream Processing Applications
Industry experts discuss best practices for selecting a separation technology.
By Caroline Hroncich
Process chromatography has changed significantly since it was first introduced to the biop…
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Tools for Continuous Bioprocessing Development
Could perfusion microbioreactors bring more agility to biomanufacturing?
By Rajeev J. Ram
In semiconductor manufacturing, for example, a thorough understanding of process variation allows co…
Article
Selecting a Comprehensive Bioburden Reduction Plan
Process maps and risk assessments are among the valuable tools operators can apply to reduce the risk of microbial contamination.
By Randi Hernandez
There are multiple variables to consider …