Search results for " assays"
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Biacore™ Analytical Services from Fast Trak™
You can outsource your biophysical screening and characterization assays by working with Cytiva’s Fast Trak™ team. The team is experienced in developing and optimizing label-free assays and systems fo…
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Genetic Vaccine Platforms Demonstrate Their Potential
…developed for a genetic or platform-based vaccine, that same process and the majority of the release assays can be used for any vector or antigen. For more traditional vaccines, each process and set …
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Updating Viral Clearance for New Biologic Modalities
Generally, viral clearance methods for these processes remove known impurities, such as DNA and HCP, by using assays that were developed and evaluated for a specific cell line, says Berrie. Thus, for …
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Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
This article focuses on concentration assays used for drug product characterization and quality control.
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Witnessing Major Growth in Next-Generation Antibodies
It is important in these cases to demonstrate that undesirable side products such as CD3 homodimers are low in the final purified product through multiple assays including physicochemical tests and in…
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Generating a Fully Processed Antibody
The results indicated that one clone (#120) showed much higher expression in both assays compared with the other three clones (Figure 2, Table I). The high level of FGE expression did not significantl…
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Changing the Culture of Cell Culture: Applying Best Practices and Authentication to Ensure Scientific Reproducibility
Table II compares and contrasts the pros and cons of STR and SNP profiling assays.
Despite the widespread availability of the STR standard and its low cost, there is little evidence th…
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Biopharma Advances Demand Specialized Expertise
Reporter gene bioassays apply genetically engineered cell lines both to directly model mechanisms of action and to amplify assays for improved performance with shorter incubations and increased signal…
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DoE Provides Benefits, but Preparation Is Necessary
For spectral data from characterization assays, Janssen calculates the Center of Spectral Mass Wavelength (or Mean Center Mass), which allows the creation of a relative stability profile for a given s…
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Elucidating Biosimilars Characterization
Comparison of analytical data forms the case for proving whether two molecules are structurally similar or not; however, data from cell-based potency and bioequivalence assays will also be required. U…